The purpose of this study is to design and simulate a PV water pumping system at Sam Ratulangi University in Indonesia. The methods employed in this study consist of a literature review, design, and simulation using HOMER (Hybrid Optimization of Multiple Energy Resources) software. The comparison between PV water pumps and dieselpowered water pumps is analysed in terms of net present cost, cost of energy (COE), and emissions to meet the water requirements in the laboratory. The simulation results are based on two design scenarios for a solar photovoltaic water pumping system at a laboratory scale. In Scenario 1, the system has a daily load of 1.5 kWh/day, 0.52 kW PV modules, 4 batteries of 80 Ah each, and a 1 kW inverter. In Scenario 2, the system has a daily pump load of 2.5 kWh/day, 0.87 kW PV modules, 4 batteries of 80 Ah each, and a 1 kW inverter. The results indicate that the utilization of solar energy to power a PV water pumping system performs well and serves as a case study showcasing the use of solar energy. Further studies on the application of PV water pump should be implemented and tested to evaluate the system’s performance.