Design and numerical-phase analysis of an SPR system for direct detection of SARS-CoV-2 virus in pharyngeal swab solution

Liu, Yansheng; Deng, Junpeng; Jia, Xiaobo; Zhou, Jin; Li, Hongli; Wang, Xiaohong; Chen, Yating; Qin, Zhenle; Jin, Zhichen; Wang, Guofu

doi:10.1039/d3nj05083a

New J. Chem.

2024

DOI: 10.1039/d3nj05083a

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Design and numerical-phase analysis of an SPR system for direct detection of SARS-CoV-2 virus in pharyngeal swab solution

Yansheng Liu,

Junpeng Deng,

Xiaobo Jia

et al.

Abstract: Quick and highly sensitive detections of the SARS-CoV-2 virus can efficiently reduce the possibility of viral spreading. In this study, a differential-phase surface plasmon resonance (SPR) biosensor is constructed to...

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Optical biosensors for diagnosis of COVID-19: nanomaterial-enabled particle strategies for post pandemic era

Tekin,

Kul,

Sagdic

et al. 2024

Microchim Acta

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The COVID-19 pandemic underlines the need for effective strategies for controlling virus spread and ensuring sensitive detection of SARS-CoV-2. This review presents the potential of nanomaterial-enabled optical biosensors for rapid and low-cost detection of SARS-CoV-2 biomarkers, demonstrating a comprehensive analysis including colorimetric, fluorescence, surface-enhanced Raman scattering, and surface plasmon resonance detection methods. Nanomaterials including metal-based nanomaterials, metal–organic frame–based nanoparticles, nanorods, nanoporous materials, nanoshell materials, and magnetic nanoparticles employed in the production of optical biosensors are presented in detail. This review also discusses the detection principles, fabrication methods, nanomaterial synthesis, and their applications for the detection of SARS-CoV-2 in four categories: antibody-based, antigen-based, nucleic acid–based, and aptamer-based biosensors. This critical review includes reports published in the literature between the years 2021 and 2024. In addition, the review offers critical insights into optical nanobiosensors for the diagnosis of COVID-19. The integration of artificial intelligence and machine learning technologies with optical nanomaterial-enabled biosensors is proposed to improve the efficiency of optical diagnostic systems for future pandemic scenarios. Graphical Abstract

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Optical biosensors for diagnosis of COVID-19: nanomaterial-enabled particle strategies for post pandemic era

Tekin,

Kul,

Sagdic

et al. 2024

Microchim Acta

View full text Add to dashboard Cite

show abstract

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Design and numerical-phase analysis of an SPR system for direct detection of SARS-CoV-2 virus in pharyngeal swab solution

Abstract: Quick and highly sensitive detections of the SARS-CoV-2 virus can efficiently reduce the possibility of viral spreading. In this study, a differential-phase surface plasmon resonance (SPR) biosensor is constructed to...

Cited by 1 publication

References 49 publications

Optical biosensors for diagnosis of COVID-19: nanomaterial-enabled particle strategies for post pandemic era

Optical biosensors for diagnosis of COVID-19: nanomaterial-enabled particle strategies for post pandemic era

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