2022
DOI: 10.1039/d1nj04543a
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Design and synthesis of leucylaniline derivatives as leucyl-tRNA synthetase inhibitors

Abstract: By simulating the structure of Leu-AMP, an intermediate of tRNA synthesis, 26 leu-arylamine derivatives were designed and synthesized by retaining leucine and replacing adenosine phosphate with amido-substituted aniline. All compounds...

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