Design and Validation of a Low-Cost Non-Invasive Device to Detect Overnight Hypoglycemia

Abstract

Research in the field of blood glucose monitoring systems has led to incredible advancements over the past several decades. The blood glucose level of a diabetic patient is vital to monitor since large swings in blood sugar can cause life threatening damage to the individual. The importance of blood glucose monitoring increases when a patient experiences hypoglycemia, which can be very dangerous. The objective of this project is to create a low cost portable device that utilizes the modular bio-signal sensor kit BITalino and Arduino Uno microcontroller to measure and process the electrodermal activity (EDA) and electrocardiography (ECG) signals that can be associated with a drop in the subject’s blood glucose level to detect hypoglycemia in diabetics.

Sense and Learn: Recent Advances in Wearable Sensing and Machine Learning for Blood Glucose Monitoring and Trend-Detection

“…The study revealed that bioimpedance plays a correcting role in the prediction when paired with other sensors. Bioimpedance of the skin has also been used to detect nocturnal hypoglycemic events ( Lesko et al, 2018 ). Another study investigated the galvanic skin response (GSR) and correlated it with blood glucose levels ( Snekhalatha et al, 2018 ), where a device was developed to acquire the GSR resistance and voltage data from 100 participants (i.e., 50 with diabetes).…”

Measuring Biosignals with Single Circuit Boards

“…Da Silva et al, e.g., described a development platform aiming at making physiological measurements available “for everyone” [ 1 ]. The group developed the low-cost modular biosignal acquisition hardware platform “BITalino” to enable building biomedical devices in an easier and more reliable way [ 31 , 32 , 33 , 34 , 35 , 36 , 37 ]. Other specially designed hardware for biosignal detection include, e.g., the Olimex shield for ECG and EMG measurements, compatible with Arduino like development boards [ 38 , 39 ].…”