Design, Building and Study of a Small-size Portable Thermoelectric Refrigerator for Vaccines

Ivanov, Kaloyan; Belovski, Ivaylo; Aleksandrov, Anatoliy

doi:10.1109/elma52514.2021.9503057

Cited by 3 publications

(2 citation statements)

References 2 publications

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“…Though a refrigerator can be put on a UAV, the weight and power requirements that significantly cut down the range do not make this an attractive solution [15]. While there are multiple cooling methods [28] (see Table A1), thermoelectric modules using the Peltier effect are ideally suited because they are solid-state and light weight [29][30][31][32]. Furthermore, since a heavier battery would be required to drive the Peltier over longer flying distances, cooling requirements can often result in a tradeoff with the achievable flying time.…”

Section: Introductionmentioning

confidence: 99%

Design and Characterization of an Active Cooling System for Temperature-Sensitive Sample Delivery Applications Using Unmanned Aerial Vehicles

Pamula,

Ramachandran

2024

Drones

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The transport of temperature-sensitive biological samples (blood, medicines, patient samples, vaccines, organs, etc.) to hard-to-reach places remains a challenge. This is especially true in places where infrastructure is limited, for which the use of unmanned aerial vehicles (UAVs) is an attractive solution. In this project, a cooling system compatible with on-board drone applications for the delivery of samples that require cold temperature storage and transportation was built, tested, and characterized. Specifically, a miniature polystyrene cooling unit with Peltier coolers was designed and built, enabling temperatures as low as −10 °C within the unit to be achieved. Further, passive and active cooling control strategies including the use of active feedback-control were explored to achieve a consistent temperature range between 2 °C and 8 °C. Finally, calculations of on-board power and battery weight required to achieve target cooling performance as a function of ambient environmental conditions are presented. Overall, this study presents an important step towards the design and development of drone-based technologies for temperature-sensitive sample delivery.

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Section: Introductionmentioning

confidence: 99%

Design and Characterization of an Active Cooling System for Temperature-Sensitive Sample Delivery Applications Using Unmanned Aerial Vehicles

Pamula,

Ramachandran

2024

Drones

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“…In the past, many scientific groups have tried portable refrigerators, especially for vaccine transportation and preservation for short durations 9 , 10 . Improved ideas of solar power-based portable refrigerators have also been reported 11 – 13 .…”

Section: Introductionmentioning

confidence: 99%

Emvolio - A battery operated portable refrigerator preserves biochemical and haematological integrity of biological samples in preclinical studies

Maity,

Aakriti,

Manandhar

et al. 2023

F1000Res

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Background: Emvolio is a non-medical device, indigenously developed portable refrigeration for maintaining the internal temperature 2–8˚C. The Indian Patent Office has granted patent for applications such as preservation and transport of medicines, vaccines, food, beverages, dairy etc. Further, use of Emvolio can be utilized in transport and store biologicals to preserve their biochemical and cellular integrity. The objective of this study was to evaluate the biochemical and haematological integrity of biological samples such as rat blood, serum and liver. Methods: The steady temperature was maintained inside the Emvolio, and it was compared to that of thermocol and polypropylene boxes aided with frozen gel packs. The blood and liver samples were isolated from Wistar rats and kept in Emvolio, thermocol and polypropylene boxes for 10 hrs, and the temperature was monitored. The blood parameters, namely red blood cells (RBC), white blood cells (WBC), platelets, haematocrit, haemoglobin, mean corpuscular volume (MCV), mean corpuscular haemoglobin concentration (MCHC) and red cell distribution width (RDW), serum parameters like alanine transaminase, alkaline phosphatase, total protein, albumin, creatine kinase, blood urea nitrogen and liver parameters like superoxide dismutase (SOD), glutathione (GSH), catalase were estimated and compared. Results: Emvolio maintained a constant inner temperature range of 2–8˚C, whereas a significant temperature variation was seen in thermocol and polypropylene boxes. There was no significant deviation in the parameters tested when samples were kept in Emvolio for six hours compared to the zero hour readings. In contrast, there was a significant deviation among the parameters for the samples kept in thermocol and polypropylene boxes for six hours compared to zero hour parameters. Conclusions: Emvolio maintained constant temperature and preserved the biological integrity of rat blood, serum and liver. Thus, Emvolio can be efficiently used as a biological sample carrier, especially in preclinical studies.

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Simulation Verification of Studies of Thermoelectric Cooling System

Ivanov,

Belovski

2024

2024 9th International Conference on Energy Efficiency and Agricultural Engineering (EE&AE)

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Design, Building and Study of a Small-size Portable Thermoelectric Refrigerator for Vaccines

Cited by 3 publications

References 2 publications

Design and Characterization of an Active Cooling System for Temperature-Sensitive Sample Delivery Applications Using Unmanned Aerial Vehicles

Design and Characterization of an Active Cooling System for Temperature-Sensitive Sample Delivery Applications Using Unmanned Aerial Vehicles

Emvolio - A battery operated portable refrigerator preserves biochemical and haematological integrity of biological samples in preclinical studies

Simulation Verification of Studies of Thermoelectric Cooling System

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