Design, construction, and evaluation of a dynamic MR compatible cardiac left ventricle model

Dieringer, Matthias A.; Hentschel, Jan; Quadros, Thiago de; Knobelsdorff‐Brenkenhoff, Florian von; Hoffmann, Werner; Niendorf, Thoralf; Schulz‐Menger, Jeanette

doi:10.1118/1.4736954

Cited by 7 publications

(9 citation statements)

References 44 publications

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“…Our results are limited by the fact that our setting did not include MR-independent flow quantification as a reference. However, the setting has been validated previously [35] and the flow was kept constant to meet the requirements for this study.…”

Section: Discussionmentioning

confidence: 99%

Effects of heart valve prostheses on phase contrast flow measurements in Cardiovascular Magnetic Resonance – a phantom study

Richau

Dieringer

Traber

et al. 2016

Journal of Cardiovascular Magnetic Resonance

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BackgroundCardiovascular Magnetic Resonance is often used to evaluate patients after heart valve replacement. This study systematically analyses the influence of heart valve prostheses on phase contrast measurements in a phantom trial.MethodsTwo biological and one mechanical aortic valve prostheses were integrated in a flow phantom. B0 maps and phase contrast measurements were acquired at a 1.5 T MR scanner using conventional gradient-echo sequences in predefined distances to the prostheses. Results were compared to measurements with a synthetic metal-free aortic valve.ResultsThe flow results at the level of the prosthesis differed significantly from the reference flow acquired before the level of the prosthesis. The maximum flow miscalculation was 154 ml/s for one of the biological prostheses and 140 ml/s for the mechanical prosthesis. Measurements with the synthetic aortic valve did not show significant deviations. Flow values measured approximately 20 mm distal to the level of the prosthesis agreed with the reference flow for all tested all prostheses.ConclusionsThe tested heart valve prostheses lead to a significant deviation of the measured flow rates compared to a reference. A distance of 20 mm was effective in our setting to avoid this influence.

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Section: Discussionmentioning

confidence: 99%

Effects of heart valve prostheses on phase contrast flow measurements in Cardiovascular Magnetic Resonance – a phantom study

Richau

Dieringer

Traber

et al. 2016

Journal of Cardiovascular Magnetic Resonance

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“…Phantom experiments using conventional FSE variants and SCSE-FSE were performed using (i) a stationary object and (ii) a dynamic model of the left ventricle [36]. For the stationary object a spherical phantom (inner diameter = 15 cm, D165, Siemens Healthcare, Erlangen, Germany) was used.…”

Section: Methodsmentioning

confidence: 99%

“…For the dynamic phantom an MR compatible left ventricle model was employed [36]. For this purpose an artificial ventricle was formed of silicon based on the geometric approximation of a paraboloid.…”

Section: Methodsmentioning

confidence: 99%

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Accelerated Fast Spin-Echo Magnetic Resonance Imaging of the Heart Using a Self-Calibrated Split-Echo Approach

et al. 2014

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PurposeDesign, validation and application of an accelerated fast spin-echo (FSE) variant that uses a split-echo approach for self-calibrated parallel imaging.MethodsFor self-calibrated, split-echo FSE (SCSE-FSE), extra displacement gradients were incorporated into FSE to decompose odd and even echo groups which were independently phase encoded to derive coil sensitivity maps, and to generate undersampled data (reduction factor up to R = 3). Reference and undersampled data were acquired simultaneously. SENSE reconstruction was employed.ResultsThe feasibility of SCSE-FSE was demonstrated in phantom studies. Point spread function performance of SCSE-FSE was found to be competitive with traditional FSE variants. The immunity of SCSE-FSE for motion induced mis-registration between reference and undersampled data was shown using a dynamic left ventricular model and cardiac imaging. The applicability of black blood prepared SCSE-FSE for cardiac imaging was demonstrated in healthy volunteers including accelerated multi-slice per breath-hold imaging and accelerated high spatial resolution imaging.ConclusionSCSE-FSE obviates the need of external reference scans for SENSE reconstructed parallel imaging with FSE. SCSE-FSE reduces the risk for mis-registration between reference scans and accelerated acquisitions. SCSE-FSE is feasible for imaging of the heart and of large cardiac vessels but also meets the needs of brain, abdominal and liver imaging.

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“…14 Phantom experiments have been performed for the development, evaluation, and validation of novel MRI techniques and optimization of imaging parameters. 15,16 To validate brain MRI techniques, a dynamic phantom that simulates blood perfusion, water diffusion, and intracranial mechanical properties is required. [17][18][19][20][21][22] Although these factors depend on each other, there have been no reports on the development of a multipurpose MRI phantom for assessing these relationships under certain conditions, in which only one of the factors is variable and the others are kept constant.…”

Section: Introductionmentioning

confidence: 99%

Technical Note: Development of a cranial phantom for assessing perfusion, diffusion, and biomechanics

et al. 2017

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Design, construction, and evaluation of a dynamic MR compatible cardiac left ventricle model

Abstract: We developed a controllable left ventricle model resembling MR signal characteristics of human myocardium, including pathological conditions, and allowing for the replication of contraction and flow paradigms.

Cited by 7 publications

References 44 publications

Effects of heart valve prostheses on phase contrast flow measurements in Cardiovascular Magnetic Resonance – a phantom study

Effects of heart valve prostheses on phase contrast flow measurements in Cardiovascular Magnetic Resonance – a phantom study

Accelerated Fast Spin-Echo Magnetic Resonance Imaging of the Heart Using a Self-Calibrated Split-Echo Approach

Technical Note: Development of a cranial phantom for assessing perfusion, diffusion, and biomechanics

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