Many design optimization problems have problems that seek fast, efficient and reliable based solutions. In such cases, artificial intelligence-based modeling is used to solve costly and complex problems. This study is based on the modeling of a multiband helical antenna using the Latin hypercube sampling (LHS) method using a reduced data enhanced multilayer perceptron (eMLP). The proposed helical antenna is dual-band and has resonance frequencies of 2.4 GHz and 2.75 GHz. The enhanced structure of the artificial neural network (ANN) was tested using 4 different training algorithms and a maximum of 10 different MLP architectures to determine the most suitable model in a simple and quick way. Then, performance comparison with other ANN networks was made to confirm the success of the model. Considering the high cost of antenna simulations, it is clear that the proposed model will save a lot of time. In addition, thanks to the selected sampling model, a wide range of modeling can be done with minimum data. When the target and prediction data are compared, it is seen that these data overlap to a large extent. As a result of the study, it was seen that the ANN modeling and the 125 samples used, were as accurate as an electromagnetic (EM) simulator for other input parameters in a wide range selected.