Design of 99mTc-labeled zinc-chelating imaging probe for SPECT imaging of the pancreas

Design, synthesis, and biological evaluation of a 99mTc-labeled small-molecule tracer for PD-L1 imaging

“…[3][4][5][6] An indirect correlation exists between the expression level of PD-L1 on the tumor surface and the effectiveness of PD-1/PD-L1 checkpoint inhibitor therapy. [7][8][9] Therefore, the expression level of PD-L1 on the tumor surface was acknowledged as an important indicator for guiding the use of PD-1/PD-L1 checkpoint inhibitors.…”