The subject of study in this article is a method for remote diagnostics, reprogramming and reconfiguration of nodes of embedded and small-sized systems. The goal is to increase the reliability characteristics of systems built on the basis of microprocessor solutions. The task is: to consider the existing methods of communication of the MC set in the system with the possibility of specifying the requirements; consider and analyze the existing means of remote reprogramming of individual MCs as part of the target system; to consider methods of adding redundancy to the MC connection scheme for the possibility of reconfiguration; describe the elements of the method and sequence of development of systems that provide for the possibility of remote diagnostics, reprogramming and reconfiguration of their individual nodes. According to the tasks, the following results were obtained. The existing methods and equipment for communication of the MC set are analyzed. Possible technical solutions and theoretical foundations of intra-system reprogramming of system nodes based on MK are analyzed. The technical properties of one of the available industrial technologies, which contain crystals and development media, are presented, with the aim of finding properties that will allow expanding the capabilities of the created systems in terms of increasing reliability and energy efficiency. It is proposed to use a modified bootloader to organize the possibility of communication and reprogramming over one communication line. A set of steps is proposed for finding options for building a circuit with hardware redundancy. Conclusions. The idea of reprogramming and diagnostics of system nodes along one line using ready-made industrial components (COTS) based on microcontrollers and development tools is proposed, which makes it possible to make their development cheaper. The proposed elements of the method of remote diagnostics, reprogramming and reconfiguration of individual nodes of the built-in system based on MC. A practical example of the implementation of the concepts discussed in the article, including its reconfiguration, is presented; a diagram of the device before and after its reconfiguration is given. The practical significance of this research lies in the possibility of building and configuring a system from many separate nodes based on microcontrollers.