This paper aims to design a stable, reliable, energy-efficient yet low-cost structural health monitoring (SHM) system for bridges in remote regions. First, the integrated system design was adopted based on the Linux architecture, and the power-efficient opensource hardware was taken as the mini Linux PCs on the bridge site. Next, several sensor subsystems were integrated physically via the Ethernet, while nine core software modules were developed based on opensource software and integrated into a logical whole. The stability of the system was improved through dual PC redundancy and intelligent fault diagnosis. The data collected by sensors were analyzed in real time and only the valid data and alarms were transmitted to the remote monitoring center. In addition, the remote transmission and active control were completed, with the aid of 3G/4G router, VPN and reverse SSH tunneling. In this way, the author developed an easy-to-maintain and cost-efficient SHM system. Finally, the effectiveness of the system was verified through the application in a bridge on an expressway in Yunnan Province, China. The results fully demonstrate the robustness, accuracy and cost effectiveness of the proposed system. This research fills up the gap in Linux-based SHM system design for bridges in remote regions, providing a reliable and advanced reference for the construction of bridge SHM systems.