“…very large scale integration (VLSI), special purpose hardware (SPH), and graphical processing unit (GPU)-based and field programmable gate array (FPGA)-based methods for simulating biological dynamics. VLSI designs can be more realistic because of the capacity to implement nonlinear models in a straightforward manner (Fieres, Schemmel, & Meier, 2008;Lewis & Renaud, 2007;Mahowald & Douglas, 1991;Renaud, Tomas, Bornat, Daouzli, & Saighi, 2007;Tomas, Bornat, Saighi, Levi, & Renaud, 2006), but the high costs and long development time of this approach limit its applications. SPH-based design has been employed to implement neurobiological functions (Furber et al, 2013;Furber, Temple, & Brown, 2006), but it is also affected by high costs and long development time.…”