Design of a New Risk Score in Critical Limb Ischaemia: The ERICVA Model

Abstract

The ERICVA model has a good predictive capacity for death and/or major amputation in the clinical setting, and is better than the PREVENT III and Finnvasc scores.

Risk stratification for low extremity amputation in critical limb ischemia patients who have undergone endovascular revascularization

“…[13,14,15,21,22,23,24,25] Findings of the present study are consistent with several of these previous studies that also identified that WBC, PLR levels, and RC at hospital admission were important risk factors for LEA. [10,13,14]…”

“…[9,10,11,13,14,15,16,20,21,22,23,24,25,26,27] Results of studies designed to assess the risk of LEA in CLI patients following bypass surgery have also been reported previously. [13,14,15,21,22,23,24,25] Findings of the present study are consistent with several of these previous studies that also identified that WBC, PLR levels, and RC at hospital admission were important risk factors for LEA. [10,13,14]…”

“…Brizuela Sanz et al developed the ERICVA model to estimate the 1-year AFS in CLI patients receiving either open or endovascular revascularization. Factors associated with major amputation and/or death in that model were cerebrovascular disease, prior contralateral major amputation, diabetes mellitus, dialysis, chronic obstructive pulmonary disease, cancer, hematocrit <30%, neutrophil/lymphocyte ratio >5, the absence of arterial Doppler signal at the ankle, emergency admission, and RC 6 [13] …”

“…Several scoring systems have been developed and biomarkers identified with the aim of improving the ability to predict functional status and to select patients who may benefit from revascularization or those for whom primary amputation or palliation should be considered. [9,10,11,12,13,14,15,16] The present study used decision tree modeling to develop a simple risk-stratification scale to assess the benefit of EVT in CLI patients with different levels of risk for LEA.…”

Midterm Outcomes After Infrapopliteal Interventions in Patients With Critical Limb Ischemia Based on the TASC II Classification of Below-the-Knee Arteries

“…Established factors associated with increased 2-year mortality in CLI patients include age, body mass index (BMI), nonambulatory status, hemodialysis, cerebrovascular disease, left ventricular ejection fraction <40%, and tissue loss. 4 Several studies have attempted to generate risk assessment models to aid in clinical decision making for management of patients with CLI, 5,6 but none of these models currently incorporates angiographic information. While it has been suggested that distal PAD is associated with unique characteristics and worse survival outcomes compared to proximal disease, even after controlling for typical risk factors, 7 the impact of lesion location and extent on outcomes in CLI remains uncertain.…”