SUMMARYA wireless body area network (WBAN) is a radio-frequency-based wireless communication technology that consists of a number of different sensor and actuator nodes interconnected with a body gateway. Considering the constrained resources in WBAN devices, simple and noise-robust synchronization algorithms are required. Frame synchronization and frequency offset estimation are extremely important in the design of a robust WBAN receiver. In this paper, a detection strategy such as frame synchronization and frequency estimation is described in the WBAN system, which can improve the receiver performance. In doing so, algorithms are designed or chosen for the frame detection, carrier frequency offset synchronization, and joint fine-time and phase-offset estimation by exploiting the spike-like property of the physical layer convergence protocol preamble and the frame structure in the WBAN system. The performance of the WBAN synchronization receiver is verified by computer simulation.