Design of a sensing glass fiber with specific refractive-index composition for a system with 1.3 μm wavelength light source

Komachiya, Masahiro; Fumino, T.; Sakaguchi, T.; Watanabe, Shigetaka

doi:10.1016/s0924-4247(99)00230-7

Cited by 1 publication

(1 citation statement)

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“…Since tissue analysis and its subsequent accurate extraction are required, one has to reconsider the ideal approach to the tissue based on the design constraints of both the laparoscope and the imaging technology. Once a thick glass-fiber bundle of a large bending radius [20] is integrated into a long, slender tubular geometry of a laparoscope's shaft, the only possible way the fibers can then guide the signal is frontally and coaxially with the instrument itself. Furthermore, in order to ensure an accurate and rapid succession of actions at reduced complexity, the mechanical biopsy should follow the direction of the preceding optical measurements.…”

Section: Minimal Tissue Deformation Approach Towards Laparoscopicmentioning

confidence: 99%

Bioinspired Spring-Loaded Biopsy Harvester—Experimental Prototype Design and Feasibility Tests

Jelínek

Smit

Breedveld

2014

Journal of Medical Devices

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Current minimally invasive laparoscopic tissue–harvesting techniques for pathological purposes involve taking multiple imprecise and inaccurate biopsies, usually using a laparoscopic forceps or other assistive devices. Potential hazards, e.g., cancer spread when dealing with tumorous tissue, call for a more reliable alternative in the form of a single laparoscopic instrument capable of repeatedly taking a precise biopsy at a desired location. Therefore, the aim of this project was to design a disposable laparoscopic instrument tip, incorporating a centrally positioned glass fiber for tissue diagnostics; a cutting device for fast, accurate, and reliable biopsy of a precisely defined volume; and a container suitable for sample storage. Inspired by the sea urchin's chewing organ, Aristotle's lantern, and its capability of rapid and simultaneous tissue incision and enclosure by axial translation, we designed a crown-shaped collapsible cutter operating on a similar basis. Based on a series of in vitro experiments indicating that tissue deformation decreases with increasing penetration speed leading to a more precise biopsy, we decided on the cutter's forward propulsion via a spring. Apart from the embedded spring-loaded cutter, the biopsy harvester comprises a smart mechanism for cutter preloading, locking, and actuation, as well as a sample container. A real-sized biopsy harvester prototype was developed and tested in a universal tensile testing machine at TU Delft. In terms of mechanical functionality, the preloading, locking, and actuation mechanism as well as the cutter's rapid incising and collapsing capabilities proved to work successfully in vitro. Further division of the tip into a permanent and a disposable segment will enable taking of multiple biopsies, mutually separated in individual containers. We believe the envisioned laparoscopic optomechanical biopsy device will be a solution ameliorating time-demanding, inaccurate, and potentially unsafe laparoscopic biopsy procedures.

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Section: Minimal Tissue Deformation Approach Towards Laparoscopicmentioning

confidence: 99%