Thailand like many other nations and governments has been plagued with countless incidents of corruption and inefficiency. However, even though the primary causes of these problems remain uncertain, there are methods available today to reduce the ongoing systemic problems. One of the potential solutions lies in using secure document interchange architecture (DIA) with blockchain technology. Using a quantitative research design and cluster sampling across 20 Thai ministries and related agencies, 500 individuals eventually participated in the study. A five-level scale questionnaire was used as the research instrument. The structural equation model (SEM) was analysed to validate the consistency of the empirical data. The results of the research indicated that after adjusting the SEM by increasing the relationship between the errors, the consistency with the empirical data of the model was very good. Of the eight hypotheses examined, all were found to be positive. However, social and cultural aspects (SCA) had the greatest positive influence on strategy/policies/legal approaches (SPL) (r = 0.72*). This was closely followed by SPL’s influence on secure electronic transaction DIA (SET) (r = 0.68*), and technology (TEC) on security semantics (SEC) (r = 0.62*). However, SEC was deemed to have the least influence on secure electronic transaction DIA (SET) (r = 0.31*). Overall, there was a high level of satisfaction with the prototype system, with the architectural efficiency showing networked integrity while verifying and authenticating with the accuracy of the electronic documents. Also from the use of electronic signatures, electronic documents could be verified and authenticated as well. Networked integrity was also proven as the DIA system could validate the accuracy and authenticity of electronic documents.