There are many remote buildings that cannot be supplied by alternating electricity of the utility grid. Due to this, this study proposes adopting Direct Current (DC) appliances for a stand-alone remote building. Direct Current can be supplied from a suitable photovoltaic array which can harvest renewable solar energy. This proposal guarantees an efficient power system by removing the necessity of including an inverter, power filter, insulation transformer, and a complicated controller, which are usually needed for producing Alternating Current (AC) power to feed AC loads using a PV system. When the proposal is applied, the PV system will be more efficient, simple, affordable, and more compact. A detailed power requirement calculation for a typical house uses DC appliances, generalized steps to design a suitable PV array, and an Artificial Neural Network (ANN) algorithm for guaranteeing Maximum Power Point Tracking (MPPT); all of which are introduced for remote buildings. The main contribution of this paper is proposing an integrated design of a DC unit of 11 kW·h PV system for stand-alone buildings that eliminates three stages that improves the system performance compared to AC unit. The introduced study includes PV array calculation based on PV module of 220 W with an intelligent algorithm of four layers. The Mean Squared Error (MSE) of the proposed ANN equals 2.7107 × 10−5 to guarantee a fast and accurate MPP tracking for continuously harvesting maximum power from the incident sunlight. An energy storage unit of 12 batteries 12 V/150 Ah of matrix dimensions 3 × 4 is designed in the DC unit for energy saving to feed the DC appliances during night hours. MATLAB/Simulink Version R2015b is used to simulate the introduced DC power unit and collect the testing records for analyzing the unit performance.