Hemodialysis treatment in specialized clinics within the same hospital significantly impacts environmental water health due to contaminated wastewater. The issues observed included changes in electrical conductivity, the presence of dangerous bacterial loads, toxicity from heavy metals, total cyanide content, and helminth parasite eggs. The level of damage is dependent on the patient’s health under treatment. This research will use a modular system that employs electrocoagulation and electro‐oxidation processes at the laboratory and pilot levels to treat hemodialysis wastewater using synthetically prepared and real samples extracted from local clinics. The results showed that these hybrid systems improved various physicochemical parameters. With these results and the experimental conditions used, the proposed treatment system was modeled using the GPS‐X program, and it was concluded that the modular system used and the electrocoagulation /electro‐oxidation/activated carbon configuration is suitable for treating wastewater from hemodialysis and that scaling up this process to facilities that have dialysate machines more advanced than those considered in this work is possible.