Design of enzyme@metal organic framework composites with thermo-responsivity for colourimetric detection of glucose

Tajwar, Muhammad Ali; Cheng, Cheng; Qi, Li

doi:10.1039/d3nr03514j

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…The goal for designing the glucose-responsive hydrogel systems was to capitalize on variations in glucose levels for targeted drug release, a concept highly relevant for diabetes management [ 210 ]. Such systems have typically incorporated materials which can react to specific glucose concentrations, employing elements like hydrogels containing glucose oxidase (GOx) or polymers sensitive to glucose levels, such as those with conjugated phenolic compounds [ 211 , 212 ]. A notable development has been a soluble thioctic acid-modified chitosan hydrogel.…”

Section: Advantages Of Hydrogel-exosome Systems For Tissue Engineeringmentioning

confidence: 99%

Hydrogel-exosome system in tissue engineering: A promising therapeutic strategy

Fan,

Pi,

Zou

et al. 2024

Bioactive Materials

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Section: Advantages Of Hydrogel-exosome Systems For Tissue Engineeringmentioning

confidence: 99%

Hydrogel-exosome system in tissue engineering: A promising therapeutic strategy

Fan,

Pi,

Zou

et al. 2024

Bioactive Materials

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Immobilized Multi‐Enzyme/Nanozyme Biomimetic Cascade Catalysis for Biosensing Applications

Cai,

Huang,

Zhu

2024

Adv Healthcare Materials

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Multiple enzyme‐induced cascade catalysis has an indispensable role in the process of complex life activities, and is widely used to construct robust biosensors for analyzing various targets. The immobilized multi‐enzyme cascade catalysis system is a novel biomimetic catalysis strategy that immobilizes various enzymes with different functions in stable carriers to simulate the synergistic catalysis of multiple enzymes in biological systems, which enables high stability of enzymes and efficiency enzymatic cascade catalysis. Nanozymes, a type of nanomaterial with intrinsic enzyme‐like characteristics and excellent stabilities, are also widely applied instead of enzymes to construct immobilized cascade systems, achieving better catalytic performance and reaction stability. Due to good stability, reusability, and remarkably high efficiency, the immobilized multi‐enzyme/nanozyme biomimetic cascade catalysis systems show distinct advantages in promoting signal transduction and amplification, thereby attracting vast research interest in biosensing applications. This review focuses on the research progress of the immobilized multi‐enzyme/nanozyme biomimetic cascade catalysis systems in recent years. The construction approaches, factors affecting the efficiency, and applications for sensitive biosensing are discussed in detail. Further, their challenges and outlooks for future study are also provided.

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Design of enzyme@metal organic framework composites with thermo-responsivity for colourimetric detection of glucose

Abstract: Enzyme immobilization on metal-organic frameworks (MOFs) has interested researchers in recent decades due to the outstanding characteristics of MOFs. However, despite some enzyme@MOF composites exhibiting better tolerance, stability and catalysis...

Cited by 2 publications

References 25 publications

Hydrogel-exosome system in tissue engineering: A promising therapeutic strategy

Hydrogel-exosome system in tissue engineering: A promising therapeutic strategy

Immobilized Multi‐Enzyme/Nanozyme Biomimetic Cascade Catalysis for Biosensing Applications

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