Design of nanorobots for exposing cancer cells

Abstract

We discuss in detail, the design of a nanorobot that can navigate, detect cancer cells in the blood and actuate the exposure of drugs. The nanorobot is designed with blood energy harvesting capability and the accumulation of electricity in a capacitor, which forms the main body of the nanorobot. Glucose hunger-based cancer detectors immobilized on a carbon nanotube sensor, reduces its electrical resistance when attached to a cancer cell. This mechanism in turn allows electric current to activate a nano-electrical-mechanical relay (mechanical transistor) to break the chamber ceiling exposing a drug identified by the immune system for cell elimination. This concept is in line with the effort to design an autonomous computational nanorobot for in vivo medical diagnosis and treatment. We present this facile approach to design a collective system to visualize the programmability in nanorobots. The calculations and simulation results provide a proof-of-concept towards a plausible implementation. Through this work, we present an overall picture towards an inorganic autonomous computational nanorobot for cancer diagnosis and treatment.

An Exploratory Review of Current Trends in Nanodentistry

“…They use glucose or natural body sugars and oxygen as a source for propulsion. 8 Each nanorobot could be modified with specific functions depending on the biochemical stimulus provided. 1 Nanorobots are expected to provide advances in medicine through miniaturization from microelectronics to nanoelectronics.…”

Towards radio transceiving in-vivo nano-robots

“…A DC source is applied to the CNT of length L and radius r c , which initiates the field emission current, I fe , between the electrodes. In our previous work [10], we have provided a model of an energy harvesting nanorobot structure. We detailed our estimation of the capacitance stored in the nanorobot by considering the glucose…”

“…The cantilever is enclosed in an air-filled chamber to increase the electrical insulation and to reduce the fringing effects between the capacitive elements. Prior simulations of a glucose energy harvesting nanodevice shows the maximum amount of potential generated to be ≈ 0.2 V [26]. This result was provided as an input potential between the two electrodes, the gold coated CNT and the counter electrode.…”

“…The nanorobot is comprised of circular cylindrical bio-compatible electrodes to harvest and store charges. The charge mobility in the designed nanorobot is enabled through a bio-detection and actuation system, as described in our previous work [10]. The chamber structure shown in Fig.…”

“…Schematic of a uniform CNT cantilever oscillator COMSOL design schematic. b Maximum tip displacement of ≈ 0.74 nm for a applied DC voltage of 0.2 V, which can be harvested[26] …”