2013
DOI: 10.1070/rc2013v082n10abeh004355
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Design of photocontrolled biomolecules based on azobenzene derivatives

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Cited by 13 publications
(16 citation statements)
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“…[12][13][14][15] More complex structural processes induced by that concept include the folding/unfolding transition of relatively large proteins, 16,17 the modulation of enzymatic activity, [18][19][20] cell-cell adhesion, 21 or ion-channel activity. 3 In vivo applications became possible with the design of biocompatible azobenzene derivatives, e.g. in zebrafish embrios 22,23 or to control mitosis.…”
Section: Introductionmentioning
confidence: 99%
“…[12][13][14][15] More complex structural processes induced by that concept include the folding/unfolding transition of relatively large proteins, 16,17 the modulation of enzymatic activity, [18][19][20] cell-cell adhesion, 21 or ion-channel activity. 3 In vivo applications became possible with the design of biocompatible azobenzene derivatives, e.g. in zebrafish embrios 22,23 or to control mitosis.…”
Section: Introductionmentioning
confidence: 99%
“…The easiest way to establish such control externally is the use of molecules that possess two clearly different stable conformations that can be interchanged with an external stimulus, usually light of a given wavelength. These molecules are conveniently called photoswitches; by far the most used and well‐documented photoswitches are derivatives of azobenzene …”
Section: Introductionmentioning
confidence: 99%
“…The common method of introducing photosensitivity to biological molecules is by connection with photochromic moieties that undergo reversible changes in structure and conformation when exposed to different wavelengths of light . Azobenzene, whose trans and cis configurations can be reversibly isomerized by irradiating with UV and blue light, is one of the most commonly used photochromic moieties . As a photoswitch, azobenzene has many advantages, including ease of synthesis, fast photoisomerization, relatively high photostationary states, and photobleaching .…”
Section: Figurementioning
confidence: 99%
“…[6,7] Azobenzene, whose trans and cis configurations can be reversibly isomerized by irradiating with UV and blue light, is one of the most commonly used photochromic moieties. [8,9] As ap hotoswitch, azobenzene has many advantages,i ncluding ease of synthesis, fast photoisomerization,r elatively high photostationary states, and photobleaching. [10] Azobenzene derivatives have been used to control the structural conformation of peptides and proteins.…”
mentioning
confidence: 99%