Design of potentiostat and current mode read-out amplifier for glucose sensing

Ahmad, Riyaz; Joshi, Amit M.; Boolchandani, Dharmendar; Varma, Tarun

doi:10.1109/ises52644.2021.00026

Cited by 7 publications

(1 citation statement)

References 21 publications

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“…Additionally, FET-based biosensing is important in the medical, beverage, and food sectors, where low-cost, biocompatible, and adaptable biomolecule determination is highly demanding. We increased the drain current sensitivity of biosensors by design and modeling a novel OTFT structure using organic material (DNTT) [29], [30], [31]. The proposed device is called dielectric-modulated double gate bilayer electrodes organic thin-film transistor (DMDGBE-OTFT) because of double gate and bilayer of metal electrode for source and drain.…”

Section: Introductionmentioning

confidence: 99%

Dielectric-Modulated Double Gate Bilayer Electrode Organic Thin Film Transistor-based Biosensor for Label-Free Detection: Simulation Study and Sensitivity Analysis

Jain¹,

Joshi²

2022

Preprint

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A dielectric-modulated double gate bilayer electrodes organic thin-film transistor (DMDGBE-OTFT) based sensor is proposed for label-free biomolecule detection. The double gate of DMDGBE-OTFT is used for creating two symmetrical gates underlap regions on both sides of the organic semiconductor. The parallel immobilization of biomolecule in two gates underlaps region changes the on-current (I ON ) of the DMDGBE-OTFT. Bilayer electrode is also used for significant reduction of barrier height to enhance the performance of the proposed device. The change in the drain current has been utilized to evaluate the sensitivity of the DMDGBE-OTFT for biomolecule recognition having different dielectric constants and corresponding charge densities using 2-D physics based numerical simulation when biomolecules are immobilized in the gate underlap area. The ATLAS TCAD tool is used to investigate the sensitivity performance of the DMDGBE-OTFT. The proposed DMDGBE-OTFT has 24.2% higher sensitivity in comparison to the recently reported OTFT-based biosensors for label-free detection of biomolecules. The DMDGBE-OTFT biosensor has a lot of potential for flexible biosensing applications in the future because of its flexibility , high sensitivity,biocompatibility and low cost.

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Section: Introductionmentioning

confidence: 99%