Neural signals play a crucial role in unraveling the mysteries of the nervous system. However, due to their minute amplitudes in the range of microamperes and microvolts, recording these signals poses significant challenges, largely stemming from their vulnerability to noise interference. Thus, the development of neural signal acquisition circuits holds paramount importance. This paper presents a successful endeavor in designing an integrated circuit using 0.18um CMOS technology, which exhibits exceptional accuracy in recording neural signals. The circuit employs a combination of amplifiers and filters, while incorporating the innovative blanking technology to effectively eliminate unwanted noise. Remarkably, this design accomplishes an impressive gain of 88.437dB. Consequently, the circuit enables the accurate capture of nerve signals, thereby positioning itself as an ideal candidate for implantable neural signal detection devices. With its ability to overcome the hurdles associated with signal sensitivity and noise interference, this integrated circuit represents a significant advancement in the field of neural signal acquisition, holding immense potential for further exploration and application in neuroscientific research and medical interventions.