This paper proposes two novel predictive proportional‐integral‐derivative (PID) controllers for second‐order non‐self‐balance systems and self‐balance systems with time delays. For second‐order non‐self‐balance systems with time delays, traditional predictive PID controllers suffer from the drawback of failing to return to the setpoint after disturbances. Therefore, this paper introduces a novel double predictive PID controller, termed PPI‐PPD controller, which consists of an inner‐loop predictive PD controller and an outer‐loop predictive PI controller. In second‐order self‐balance systems encountered in practical chemical processes, time delays can lead to longer adjustment times, increased overshoot, and divergence issues. In order to solve these problems, an improved predictive PID (PPID) controller is proposed in this paper, which introduces a compensation link and an anti‐interference link in the traditional predictive PID controller. This enhancement improves the dynamic response and disturbance resistance of the control system. Simulation results demonstrate that both novel predictive PID controllers exhibit excellent control performance and robustness.