Design of supramolecular nanosheets for drug delivery applications

Abstract

Two specific concepts have emerged in the field of materials science over the last several decades: nanosheets and supramolecular polymers. More recently, supramolecular nanosheets, in which these two concepts are integrated, have attracted particular attention, and they exhibit many fascinating characteristics. This review focuses on the design and applications of supramolecular nanosheets consisting of tubulin proteins and phospholipid membranes.

Sub-100 nm carriers by template polymerization for drug delivery applications

“…39,40 A significant component of nanomedicine focuses on DDSs, featuring nano-sized, soft nanoparticles like liposomes, lipid nanoparticles, polymeric nanoparticles, polymer-drug conjugates, dendrimers, and hydrogels, alongside hard nanoparticles such as carbon nanotubes, gold nanoparticles, and metalorganic frameworks. 29,[41][42][43][44][45] Among these, nanocarriers based on polymers offer several distinct advantages such as easy synthetic methods, tunable chemical and physical properties, incorporation of both hydrophilic and hydrophobic drugs and relatively higher stability than those based on liposomes. Biodegradable units can be easily integrated into polymers that greatly contribute to the controlled drug release from the nanocarrier in a sustainable manner.…”