A railway at all stages of its life cycle (design, construction, operation) interacts with the environment. The environment can be divided into two components, which, depending on the geographical location of the area and its economic development, are characterized by their regional factors. Natural: climate, relief, geology, hydrology, etc. Economic: the development of the area, the density of population and transport networks, industry, etc. The environment affects the choice of the main technical parameters of the railway, design characteristics, methods of construction and operation, and therefore, construction and operating costs. For the analysis of regional factors, a conditional parameter is adopted, the value of which changes in the same direction as the regional parameters. The regression equation between these parameters and the construction cost of 1 km of railway in the considered areas was revealed.