Design of the safety standard at hydrofluoric acid handling facilities for risk reduction

Characteristics of nanoparticle formation and hazardous air pollutants emitted by 3D printer operations: from emission to inhalation

“…8 It is well-known that the thermal processing of polymer materials release toxic air pollutants, including carcinogens and chemicals that cause nervous system disorders. [9][10][11] The composition of the toxic air pollutants produced during the thermal heating process is very complex because of the many types of thermoplastics. 12 Furthermore, FFF-type 3D printers are known to emit particulate matter with sizes of <100 nm and volatile organic compounds (VOCs) because of lament extrusion.…”

Self-Amplified HF Release and Polymer Deconstruction Cascades Triggered by Mechanical Force

“…While HF is widely used in the synthesis of fluorine-containing compounds, such as fluoropolymers and pharmaceutical intermediates, we were drawn to its use as a versatile reagent for material remodeling. In particular, fluoride sources react readily with silica-containing materials, and this efficient characteristic has been applied in self-immolative polymers, remodeled siloxane elastomers, , vitrimer alteration, and degradable polymers. ,, The corrosiveness and toxicity of HF, however, present a safety concern for its handling and storage . We therefore set out to develop a latent source of HF that resides within a polymer until it is released in response to a mechanical signal, at which point it could be converted in situ to a fluoride salt for the uses described above.…”

“…18,35,36 The corrosiveness and toxicity of HF, 37 however, present a safety concern for its handling and storage. 38 We therefore set out to develop a latent source of HF that resides within a polymer until it is released in response to a mechanical signal, at which point it could be converted in situ to a fluoride salt for the uses described above. In designing a mechanophore for fluoride release, we considered that the addition of a methoxy substituent to a gem-dichlorocyclopropane (gDCC) mechanophore yielded a 2methoxy-substituted gem-dichlorocyclopropane (MeO-gDCC) 27 that acts as a latent source of HCl (Figure 1).…”