Abstract-Percutaneous intervention has attracted significant interest in recent years, but many of today's needles and catheters can only provide limited control of the trajectory between an entry site and soft tissue target. In order to address this fundamental shortcoming in minimally invasive surgery, we describe the first prototype of a bio-inspired multi-part probe able to steer along planar trajectories within a compliant medium by means of a novel "programmable bevel", where the steering angle becomes a function of the offset between interlocked probe segments. A kinematic model of the flexible probe and programmable bevel arrangement is derived. Several parameters of the kinematic model are then calibrated experimentally with a fully functional scaled-up prototype, which is 12 mm in diameter. A closed-loop control strategy with feed-forward and feedback components is then derived and implemented in vitro using an approximate linearization strategy first developed for car-like robots. Experimental results demonstrate satisfactory twodimensional trajectory following of the prototype (0.68 mm tracking error, with 1.45 mm STD) using an electromagnetic position sensor embedded at the tip of the probe.Index Terms-Biologically inspired robots, closed-loop control, medical robots and systems, needle steering, nonholonomic motion planning
I. INTRODUCTIONERCUTANEOUS intervention has always attracted significant interest because it is performed through the skin and, as such, it has several advantages for the patient [1]. Tumor biopsy, brachytherapy, deep brain stimulation and localized drug delivery, for instance, benefit from this operative technique to reduce tissue trauma and hospitalization time.In order to localize a lesion, preoperative planning using Computer Tomography (CT) or Magnetic Resonance (MR) Manuscript received May 14, 2010. This work was supported by the EU-FP7 Project ROBOCAST (FP7-ICT-215190) and has also received funding from the European Research Council under the European Union's Seventh Framework Programme (FP7/2007(FP7/ -2013 / ERC grant agreement n° [258642-STING].S. Y. Ko and L. Frasson are with Department of Mechanical Engineering, Imperial College London, SW7 2AZ, UK (e-mail: s.ko@imperial.ac.uk, luca.frasson07@imperial.ac.uk).F. Rodriguez y Baena is with Department of Mechanical Engineering and the Institute of Biomedical Engineering, Imperial College London, SW7 2AZ, UK (corresponding author to provide phone: +44-(0)20-7594-7046; fax: +44-(0)20-7594-1472; e-mail: f.rodriguez@imperial.ac.uk).images is often necessary. If the lesion is reachable through a straight path, a straight rigid needle can be used. For a safe operation, the location of the needle tip can be monitored by means of external markers mounted on the proximal end of the needle by relying on the fixed geometrical relationship between the base and needle point.Recently, there have been efforts to introduce steerable needles in percutaneous interventions where a straight path does not seem possible or is not safe. Steerab...