2002
DOI: 10.1016/s0144-8617(02)00029-2
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Design, preparation and assessment of citrate-linked monosaccharide cellulose conjugates with elastase-lowering activity

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Cited by 22 publications
(21 citation statements)
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“…Thus, they consist of carbon-nitrogen stretching (CN s) for amide II. The nature of the amide I and II absorbances in the lysozyme-cellulose conjugates is affected by the conformation of the protein as well as the carbonyls of the citrate carboxyl functionalities within the crosslinked cotton (Edwards et al 2002).…”
Section: Resultsmentioning
confidence: 99%
“…Thus, they consist of carbon-nitrogen stretching (CN s) for amide II. The nature of the amide I and II absorbances in the lysozyme-cellulose conjugates is affected by the conformation of the protein as well as the carbonyls of the citrate carboxyl functionalities within the crosslinked cotton (Edwards et al 2002).…”
Section: Resultsmentioning
confidence: 99%
“…In a healthy person healing occurs in 21 days from coagulation, and the remodeling phase consisting of scar transformation based on collagen synthesis continues for months following injury Cellulose (2009) 16:911-921 913 selectively bind the enzyme to the wound dressing in the presence of other wound proteins that promote wound healing. Mechanism-based dressings include and are composed of collagen and oxidized regenerated cellulose (Cullen et al 2002), nanocrystalline silver-coated high density polyethylene (Wright et al 2002), deferroxamine-linked cellulose (Meyer-Ingold et al 2000), electrophilic and ionically derivatized cotton (Edwards et al 2001), peptide (Edwards et al 1999) or carbohydrate conjugates (Edwards et al 2002), and bisphosphonate MMP inhibitors (Rayment et al 2008) and sulfonated ion exchange derivatives of hydrogel polymers (Vachon and Yager 2006). We discuss here the relative activities of two negatively charged cellulose fibers for their abilities to sequester proteases.…”
Section: Cellulose Dressing Design For Inflammatory Phase Of Wound Hementioning
confidence: 99%
“…The dressing's mechanism of action may also be through other cellular or biochemical events that modulate protease levels. Previously reported active wound dressings designed to redress the biochemical imbalance of the chronic wound in this manner are composed of collagen and oxidized regenerated cellulose, 20 nanocrystalline silver-coated high density polyethylene, 21 deferrioxamine-linked cellulose, 22 electrophilic and ionically derivatized cotton, 23 peptide 24 or carbohydrate-conjugates, 25 and sulfonated ion exchange derivatives of hydrogel polymers. 26 Cotton dressings are still a standard in chronic wound care, 23 and improvement in cotton dressing finishes to enhance absorbency, gelation, and elasticity have been reported.…”
Section: Introductionmentioning
confidence: 99%
“…26 Cotton dressings are still a standard in chronic wound care, 23 and improvement in cotton dressing finishes to enhance absorbency, gelation, and elasticity have been reported. [23][24][25]27 Here, we report the design and assessment of phosphorylated cotton wound dressings that significantly enhance the removal of both human neutrophil elastase and collagenase from wound fluid.…”
Section: Introductionmentioning
confidence: 99%