Org. Biomol. Chem.
 2024
DOI: 10.1039/d4ob01264j
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Design strategy and preliminary antiproliferative investigation of a modified lignan skeleton derived from aryne and statin

Yu Lei,
Yinshan Wen,
Xiaoliang Xu
et al.

Abstract: We have developed a novel method to synthesize modified lignan derivatives. These compounds exhibited moderate antiproliferative effects and the IC50 values were in the micromolar range.

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