Design, synthesis and antiproliferative evaluation of new acridine-thiosemicarbazone derivatives as topoisomerase IIα inhibitors

Leonel Silva Sousa, Gleyton; da Silva Honório, Thiago; de Souza Furtado, Priscila; Simon, Alice; Mendes Cabral, Lucio; Rodrigues Coutinho Pereira, Gabriel; Emanuel Ferreira Alves, Josival; Mônica Vitalino de Almeida, Sinara; Rodrigues Silva, Valdenizia; de Souza Santos, Luciano; Pereira Bezerra, Daniel; Nora Castro, Rosane; Olímpio de Moura, Ricardo; Eugen Kümmerle, Arthur

doi:10.1016/j.rechem.2024.101371

Results in Chemistry

2024

DOI: 10.1016/j.rechem.2024.101371

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Design, synthesis and antiproliferative evaluation of new acridine-thiosemicarbazone derivatives as topoisomerase IIα inhibitors

Gleyton Leonel Silva Sousa,

Thiago da Silva Honório,

Priscila de Souza Furtado

et al.

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Cited by 2 publications

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Design, synthesis and antiproliferative evaluation of new acridine-thiosemicarbazone derivatives as topoisomerase IIα inhibitors

Cited by 2 publications

References 77 publications

Coumarin-imidazopyridine hybrids and their first-in-class ZnII metal complexes as potent dual entry and replication inhibitors of Zika viral infection

Coumarin-imidazopyridine hybrids and their first-in-class ZnII metal complexes as potent dual entry and replication inhibitors of Zika viral infection

Discovery of novel thiosemicarbazone-acridine targeting butyrylcholinesterase with antioxidant, metal complexing and neuroprotector abilities as potential treatment of Alzheimer's disease: In vitro, in vivo, and in silico studies

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