Design, synthesis, and high-throughput in vitro anti-cancer evaluation of novel 4-aminopyrazolo[3,4-d]pyrimidine derivatives: potential anti-cancer candidates against UO-31 renal cancer cells

Abstract

Twenty novel 4-aminopyrazolo[3,4-d]pyrimidine core compounds were synthesized, characterized and identified as novel anti-cancer compounds. These compounds showed excellent activity against UO-31 Renal Cancer Cells.