Design, synthesis, linear and nonlinear photophysical properties of novel pyrimidine-based imidazole derivatives

Abstract

Novel pyrimidine imidazole derivatives with flexible ether chains have been synthesised and evaluated for their cell imaging performanceviaphotophysical investigations and theoretical calculations.

Small water-soluble pyrimidine hexafluorophosphate derivatives with high two-photon absorption activities in the near-IR region and their biological applications

“…On the other hand, comparison of the 2PA properties reveals the relative efficiency of the cores. The values of Fs for 6P are smaller than L1, 16 understandably due to the acceptors linked to the cores. Fs decreases by ten times when the core is changed from imidazolyl to imidazolyl-hexauorophosphate.…”

“…Clearly, the polarity of the solvent and the excitation wavelength has a signicant inuence on the action two-photon absorption cross section. Compared to the previous chromophores derived from pyrimidine, 15,16,24,25 small changes in the structure may have important implications in terms of molecular engineering for specic applications because the 2PA properties (in terms of cross sections, position of the maximum, and bandwidth), as well as the one photon and the photoluminescence characteristics can be affected considerably. Increasing the branch number results in a pronounced enhancement of the 2PA cross sections in the NIR region, which may imply that extending the p-conjugation domain is accomplished by increasing the number of branches.…”

“…15 EX-6 and EX-10 were synthesized by the Witting reaction. 15,16 The details of the synthesis and characterization data are given in the Experimental section. All compounds were characterized by elemental analyses, IR, MOLDI-TOF-MS and NMR spectral techniques.…”

“…It exhibits adequate safety, tolerability and clinical efficacy proles in preclinical and clinical trials. 16 The introduction of exible ether chains and ethoxyphenyl triphenylamine can not only increase the solubility of this molecule, but also enhance the electron-donating property of the amino group. On the other side, an issue of primary importance is the solubility of products in several common organic solvents and water.…”

N‐Ethyl Carbazole Derived D‐π‐A‐π‐D Based Fluorophores: Consolidated Spectroscopic, Viscosity and DFT Studies

“…Organic molecules with donor‐acceptor (D–A) architect find uses in the area of organic solar cells (OSCs), organic light‐emitting diodes (OLEDs), organic photovoltaics (OPVs), organic thin‐film transistors (OTFTs), two‐photon absorption (2PA), photodynamic therapy, ion‐sensing, cell imaging, fluorescent molecular rotors (FMR's) and non‐linear optical (NLO) materials . Efforts are made to diversify the D–A materials by designing and synthesizing a wide spectrum of dipolar, quadrupolar, octupolar and multi‐branched chromophores .…”