Designed formulation based on α-tocopherol anchored on chitosan microspheres for pH-controlled gastrointestinal controlled release

Prado, Alexandre G.S.; Santos, André L. F.; Nunes, Alécio R.; Tavares, Guilherme W.; Almeida, Cláudio Magalhães de

doi:10.1016/j.colsurfb.2012.02.036

Cited by 12 publications

(5 citation statements)

References 24 publications

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“…The emulsion droplets were homogeneously distributed in the film forming solution. As reported by some authors, α‐tocopherol tends to interact with the biopolymer chain of CS through hydrogen bonding between the OH groups of α‐tocopherol and NH 2 of CS, along with the CS polycationic nature, ensuring greater emulsion stability (Prado, Santos, Nunes, Tavares, & de Almeida, 2012). Figure 1b shows the formation of an intercalated structure in the bio‐nanocomposite due to the higher distances among the MMT15A lamellae in the Treatment 2 containing MMT 15A.…”

Section: Resultsmentioning

confidence: 85%

Chitosan‐nanocomposites as a food active packaging: Effect of addition of tocopherol and modified montmorillonite

Dias

Azevedo

Ferreira

et al. 2021

J Food Process Engineering

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The development of natural biodegradable polymers to partially or totally replace synthetic polymers may be advantageous in food packaging, mainly when are associated with additional features such as active packaging. This article aimed to evaluate the effect of tocopherol concentration (0, 5, 10, and 20%) and modified montmorillonite clay (MMT15A) nanoparticles (0 and 1%) on the properties of chitosan (CS) films. The addition of tocopherol provided antioxidant activity and improved the thermal stability of the films, and acted as a plasticizer, decreasing the tensile strength, elastic modulus, and glass transition temperature of the films. Although MMT15A and tocopherol did not change the water vapor permeability, an improvement of the mechanical strength and lower equilibrium moisture content was observed when compared to the treatment made with CS alone. Both MMT15A and tocopherol allowed the production of bio‐nanocomposites with thermal, morphological, mechanical, and water‐resistant properties to be used as an antioxidant in packaging materials. Practical Applications The films containing both montmorillonite (MMT15A) and tocopherol presented an improved mechanical strength, thermal stability, and antioxidant activity when compared to the films containing the only tocopherol. Therefore, it was possible to develop antioxidant chitosan films with improved properties using up to 20% tocopherol and MMT15A. At this tocopherol and MMT 15A concentrations, the films may also be used to nutritionally enrich food, adding value to the package and the conditioned product. Furthermore, the films can also be considered edible films with combined properties.

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Section: Resultsmentioning

confidence: 85%

Chitosan‐nanocomposites as a food active packaging: Effect of addition of tocopherol and modified montmorillonite

Dias

Azevedo

Ferreira

et al. 2021

J Food Process Engineering

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“…Monomer length in polyhydroxyalkanoates (PHAs) depends on the producing bacteria and molecular weights vary with growth medium conditions. For instance, high molecular weight polyhydroxyoctanoate can be produced in diethylene glycol-rich medium.In tissue engineering, PHA composites have been prepared with hydroxyapatite, bioactive glass, and glass-ceramic fillers (39)(40)(41)(42)(43)(44). It has been recently shown that the biodegradability of polyhydroxybutyrate (P3HB) and P3HB/valerate copolymers depends greatly on molecular weight, processing conditions, and crystallinity.…”

Section: Polyhydroxyalkanoates (Phas)mentioning

confidence: 99%

A review on vegetable oil based biodegradable polymers

Jakune¹,

Tegeli²,

Badewale³

2023

Int. J. Sci. Res. Arch.

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The reviewed work addressed the shift in focus from conventional polymers to bio-based and renewable polymers. This extensively discussed the values of various fatty acid components present in the oils and polymers. Areas of application of the thermosetting polymers obtained from plant seed oils were discussed. Non-biodegradable polymers are causing severe damage to the environment. To counter this, need of biodegradable polymers is gaining a rapid growth in numbers, in their applications and quantities used. In this manuscript, we have briefly described important vegetable oil derived materials such as alkyds, poly-esteramides, , polyurethanes, epoxies, polyols, along with their preparation and applications as protective coatings. A small portion of the review is also dedicated to the future perspectives in the field. In spite of their extensive utilization in the world of coatings, literature survey revealed that in the past no review has come up describing the chemistry and applications of vegetable oil polymer based coating materials. In addition, due to the oil crises worldwide, focuses from synthesizing polymers from petroleum has shifted to the synthesis of polymers from renewable resources such as vegetable oils. The use of vegetable oils in the polymer renders biodegradability to the polymer. Different researchers have used different vegetables oils like castor oil, soybean oil, & sunflower oil for synthesis of polymers and utilized them in diverse fields like biomedical, coatings, adhesives, and as structural materials. This review discusses the synthesis, characterization, degradation and applications of polymers obtained from natural oils such as castor oil, soybean oil etc.

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“…More specifically, chitosan has been reinforced with calcium phosphate nanocrystals for tissue engineering with strong adherence to natural bone [94]. Also, chitosan nano- and micro-particles have been used for drug delivery [95,96,97]. Chitosan has also been reinforced with cellulose nanocrystals [98], and nanofibers [99], leading to materials with satisfactory mechanical and water vapor barrier properties for food packaging [99].…”

Section: Bio-based Polymersmentioning

confidence: 99%

Bio-Based Polymers with Potential for Biodegradability

2016

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A variety of renewable starting materials, such as sugars and polysaccharides, vegetable oils, lignin, pine resin derivatives, and proteins, have so far been investigated for the preparation of bio-based polymers. Among the various sources of bio-based feedstock, vegetable oils are one of the most widely used starting materials in the polymer industry due to their easy availability, low toxicity, and relative low cost. Another bio-based plastic of great interest is poly(lactic acid) (PLA), widely used in multiple commercial applications nowadays. There is an intrinsic expectation that bio-based polymers are also biodegradable, but in reality there is no guarantee that polymers prepared from biorenewable feedstock exhibit significant or relevant biodegradability. Biodegradability studies are therefore crucial in order to assess the long-term environmental impact of such materials. This review presents a brief overview of the different classes of bio-based polymers, with a strong focus on vegetable oil-derived resins and PLA. An entire section is dedicated to a discussion of the literature addressing the biodegradability of bio-based polymers.

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Designed formulation based on α-tocopherol anchored on chitosan microspheres for pH-controlled gastrointestinal controlled release

Cited by 12 publications

References 24 publications

Chitosan‐nanocomposites as a food active packaging: Effect of addition of tocopherol and modified montmorillonite

Chitosan‐nanocomposites as a food active packaging: Effect of addition of tocopherol and modified montmorillonite

A review on vegetable oil based biodegradable polymers

Bio-Based Polymers with Potential for Biodegradability

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