2018
DOI: 10.1016/j.cej.2017.10.033
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Designer fibers from 2D to 3D – Simultaneous and controlled engineering of morphology, shape and size

Abstract: Topography and surface morphology of micrometer and nanometer scaled fibrous biomaterials are crucial for bioactive component encapsulation, release, promoting cell proliferation and interaction within biological environment. Specifically, for drug delivery and tissue repair applications, surface engineering provides control on both aspects in tandem. In this study, the bioactive component (ganoderma lucidum spore polysaccharide (GLSP)) was loaded into zein prolamine (ZP) fiber matrices via coaxial electrospin… Show more

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Cited by 51 publications
(41 citation statements)
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“…Thus, in this study the outer solvent was used to prevent any clinging of semi-solid CA to the spinneret, preventing blocking of the needles and ensuring a stable and continuous electrospinning process. The outer solvent should also help the electrical forces to draw the inner and middle fluids evenly during the solvent exhaustion process (Yao, et al, 2018). These two effects of the outer solvent are combined synergistially to ensure the formation of high-quality nanofibers regardless of their composition (either monolithic F1 systems or core-shell hybrids in the case of F2 to F4).…”
Section: Morphological Characteristics and Inner Structures Of The Prmentioning
confidence: 99%
“…Thus, in this study the outer solvent was used to prevent any clinging of semi-solid CA to the spinneret, preventing blocking of the needles and ensuring a stable and continuous electrospinning process. The outer solvent should also help the electrical forces to draw the inner and middle fluids evenly during the solvent exhaustion process (Yao, et al, 2018). These two effects of the outer solvent are combined synergistially to ensure the formation of high-quality nanofibers regardless of their composition (either monolithic F1 systems or core-shell hybrids in the case of F2 to F4).…”
Section: Morphological Characteristics and Inner Structures Of The Prmentioning
confidence: 99%
“…Furthermore, they have been described to strongly interact with natural polyphenols through hydrophobic interactions and hydrogen bonding (Jakobek, 2015;Siebert, Troukhanova, & Lynn, 1996), implying that the stability of electrospun protein fibers could be further improved by the addition of polyphenols as natural crosslinkers for proteins (Anvari & Chung, 2016). In particular, zein and gelatin are two proteins whose ability to form electrospun fibers has been already demonstrated (Lu et al, 2015;Yao et al, 2018). In addition, both proteins have previously shown their potential to enhance the stability of sensitive bioactive ingredients encapsulated within them through electrohydrodynamic processing (Gómez-Mascaraque et al, 2015;Gómez-Mascaraque, Perez-Masiá, González-Barrio, Periago, & López-Rubio, 2017).…”
Section: Some Of the Advantages Of Electrohydrodynamic Processing As mentioning
confidence: 99%
“…More recently, researchers have developed two-fluid side-by-side and coaxial electrospinning processes (resulting in Janus or core/shell fibers) [10][11][12][13][14][15][16], three-fluid triaxial electrospinning, and other more complicated experiments [17][18][19][20].…”
Section: Introductionmentioning
confidence: 99%