Designing and characterization of a highly sensitive and selective biosensing platform for ciprofloxacin detection utilizing lanthanum oxide nanoparticles

Chaudhary, Navneet; Yadav, Amit K.; Sharma, Jai Gopal; Solanki, Pratima R.

doi:10.1016/j.jece.2021.106771

Cited by 29 publications

(21 citation statements)

References 53 publications

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“…177 In this method, the electron movement on account of biochemical reactions, and the immobilization of biological analytes, both occur on the electrodes. [178][179][180] Based on operating principles, electrochemical biosensors are divided into four types-potentiometric, amperometric, conductimetric, and impedimetric. 181,182 The first diagnostic biosensor was established in 1967 for blood glucose levels detection employing natural human enzyme (glucose oxidase) using an electrochemical detector.…”

Section: Interleukins: Biomarkers Of Clinical Usesmentioning

confidence: 99%

Review—Interleukins Profiling for Biosensing Applications: Possibilities and the Future of Disease Detection

et al. 2022

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Interleukins (ILs) are a major subclass of cytokines which act as molecular messengers playing a role in immune system responses via cascade of signalling pathways. Belonging to the cytokine family, ILs play a crucial role in the theronostics of various diseases. Their abnormal expression leads to development of various diseases such as cancer, neurodegenerative diseases, allergies, asthma, autoimmune diseases, and other physiological abnormalities. This paves the way for exploring ILs to develop sensitive and efficient biosensors, and promoting them for clinical testing in a wide array of diseases. Furthermore, detecting the level of ILs is very important for their early diagnosis and their progression within the body, and simultaneously for possible immunotherapeutic approaches. To achieve this goal, multidisciplinary scientific approaches involving immunology, electrochemistry, nanotechnology, photometry, etc. are already being put into action. Advancements in nanoscience and nanotechnology are aiding in the development of highly sensitive biosensors for ILs detection. This review focuses on a detailed description of all presently discovered ILs and their roles in various diseases. Simultaneously, it also discusses the various electrochemical biosensors that can be employed for the detection of ILs in bodily fluids. Moreover, the role of nanomaterials in electrochemical biosensing are also discussed here.

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Section: Interleukins: Biomarkers Of Clinical Usesmentioning

confidence: 99%

Review—Interleukins Profiling for Biosensing Applications: Possibilities and the Future of Disease Detection

et al. 2022

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“…The coefficient of diffusion (represented by 'D') at the interface of the electrolyte and electrode surface comprising a redox couple was estimated using the Randles-Sevcik formula as given by eqn (8) 59,60 Ip = (2.69…”

Section: Scan Rate Studymentioning

confidence: 99%

“…The coefficient of diffusion (represented by ‘ D ’) at the interface of the electrolyte and electrode surface comprising a redox couple was estimated using the Randles–Sevcik formula as given by eqn (8) 59,60 Ip = (2.69 × 10 5 ) Cn 3/2 D 1/2 v 1/2 A where v denotes the scan rate (V s −1 ), C is the electrolyte concentration, D is the coefficient of diffusion (cm 2 s −1 ), A represents the electrode surface area (0.25 cm 2 ), n is the number of transferred electrons during the redox event, 1 and Ipa represents the peak current of the electrodes. The calculated D value for the MIP/ITO electrode was found to be higher, i.e.…”

Section: Electrochemical Studiesmentioning

confidence: 99%

A molecularly imprinted polymer based on a novel polyaniline–zinc sulfide nanocomposite for electrochemical detection of trimethylamine N-oxide

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Sajwan

Lakshmi

et al. 2022

Environ. Sci.: Nano

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“…Biosensor technologies have provided the potential to achieve the above conditions via an interdisciplinary mixture of medical science, chemistry, and nanotechnology techniques. The various advantages of biosensors are high precision, low cost, and rapid analysis applied in numerous fields, such as the fermentation industry, environmental monitoring, antibiotics detection [ 25 , 26 , 27 ], disease diagnosis [ 28 , 29 , 30 ], and medical care [ 31 ]. Biosensing technology provides significant advantages over traditional detection methods such as spectroscopy or chromatography.…”

Section: Introductionmentioning

confidence: 99%

Nanomaterial-Based Electrochemical Nanodiagnostics for Human and Gut Metabolites Diagnostics: Recent Advances and Challenges

et al. 2022

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Metabolites are the intermediatory products of metabolic processes catalyzed by numerous enzymes found inside the cells. Detecting clinically relevant metabolites is important to understand their physiological and biological functions along with the evolving medical diagnostics. Rapid advances in detecting the tiny metabolites such as biomarkers that signify disease hallmarks have an immense need for high-performance identifying techniques. Low concentrations are found in biological fluids because the metabolites are difficult to dissolve in an aqueous medium. Therefore, the selective and sensitive study of metabolites as biomarkers in biological fluids is problematic. The different non-electrochemical and conventional methods need a long time of analysis, long sampling, high maintenance costs, and costly instrumentation. Hence, employing electrochemical techniques in clinical examination could efficiently meet the requirements of fully automated, inexpensive, specific, and quick means of biomarker detection. The electrochemical methods are broadly utilized in several emerging and established technologies, and electrochemical biosensors are employed to detect different metabolites. This review describes the advancement in electrochemical sensors developed for clinically associated human metabolites, including glucose, lactose, uric acid, urea, cholesterol, etc., and gut metabolites such as TMAO, TMA, and indole derivatives. Different sensing techniques are evaluated for their potential to achieve relevant degrees of multiplexing, specificity, and sensitivity limits. Moreover, we have also focused on the opportunities and remaining challenges for integrating the electrochemical sensor into the point-of-care (POC) devices.

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Designing and characterization of a highly sensitive and selective biosensing platform for ciprofloxacin detection utilizing lanthanum oxide nanoparticles

Cited by 29 publications

References 53 publications

Review—Interleukins Profiling for Biosensing Applications: Possibilities and the Future of Disease Detection

Review—Interleukins Profiling for Biosensing Applications: Possibilities and the Future of Disease Detection

A molecularly imprinted polymer based on a novel polyaniline–zinc sulfide nanocomposite for electrochemical detection of trimethylamine N-oxide

Nanomaterial-Based Electrochemical Nanodiagnostics for Human and Gut Metabolites Diagnostics: Recent Advances and Challenges

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