2024
DOI: 10.1146/annurev-publhealth-040617-013507
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Designing Difference in Difference Studies: Best Practices for Public Health Policy Research

Abstract: The difference in difference (DID) design is a quasi-experimental research design that researchers often use to study causal relationships in public health settings where randomized controlled trials (RCTs) are infeasible or unethical. However, causal inference poses many challenges in DID designs. In this article, we review key features of DID designs with an emphasis on public health policy research. Contemporary researchers should take an active approach to the design of DID studies, seeking to construct co… Show more

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Cited by 1,065 publications
(910 citation statements)
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References 105 publications
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“…The results reveal a pattern that is similar to the preferred estimates below, and show that using time fixed effects does not statistically lead to a higher log‐likelihood value, compared to a linear trend. Consistent with the ITS and CITS exercises, the use of alternative methods to account for non‐stationarity and autocorrelation reinforces the conclusions of this paper, illustrating their robustness …”
Section: Methodssupporting
confidence: 79%
See 2 more Smart Citations
“…The results reveal a pattern that is similar to the preferred estimates below, and show that using time fixed effects does not statistically lead to a higher log‐likelihood value, compared to a linear trend. Consistent with the ITS and CITS exercises, the use of alternative methods to account for non‐stationarity and autocorrelation reinforces the conclusions of this paper, illustrating their robustness …”
Section: Methodssupporting
confidence: 79%
“…Table A.2 shows that DD is preferred to CITS; the diverging trend hypothesis does not hold statistically, leading to overfitting under CITS . An explanation why CITS performs less well here compared to other studies is perhaps the fact that the number of pre‐intervention data points in this study is too small (five data points: March‐July 2010) to properly establish pre‐intervention trends and observe trend divergence …”
Section: Methodsmentioning
confidence: 84%
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“…The cross‐sectional observations in the panel consist of the 197 most populous cities in the United States in 1990 and all other places (ie, localities other than those cities) aggregated together within each state (Table ). We employed a difference‐in‐differences approach (sometimes called a 2‐way fixed effects model), which is commonly used for identifying treatment effects when there is staggered policy implementation . As used here, this model compares the difference in homicide rates in a city before and after the implementation of a firearm law in that state to contemporaneous changes in homicide rates in cities located in states without such laws.…”
Section: Methodsmentioning
confidence: 99%
“…In Table , we used difference‐in‐differences regression analyses to evaluate the effects of screening mammography on breast cancer incidence and mortality rates. This method has been rigorously developed in the causal inference literature, but its roots date back to much earlier use in public health, including in John Snow's famous studies of cholera transmission in 1850’s London . In the difference‐in‐differences method, the effect of an intervention is evaluated observationally by comparing the changes in outcomes between groups that receive the intervention and control groups that do not.…”
Section: Methodsmentioning
confidence: 99%