2007
DOI: 10.1016/j.biomaterials.2007.08.041
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Designing hydrogel adhesives for corneal wound repair

Abstract: Today, corneal wounds are repaired using nylon sutures. Yet there are a number of complications associated with suturing the cornea, and thus there is interest in an adhesive to replace or supplement sutures in the repair of corneal wounds. We are designing and evaluating corneal adhesives prepared from dendrimers -single molecular weight, highly branched polymers. We have explored two strategies to form these ocular adhesives. The first involves a photocrosslinking reaction and the second uses a peptide ligat… Show more

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Cited by 162 publications
(144 citation statements)
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“…there is also the risk of needlestick injury to the surgeon or operating room personnel [1,6,7]. Suture areas can also be a site for infection and inflammation, which will lead to more complications and require additional treatment [6]. After operations, sutures and other fasteners have a tendency to loosen and possibly break, which entails extra treatment to fix these problems [1].…”
Section: History Of Silver Nanoparticlesmentioning
confidence: 99%
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“…there is also the risk of needlestick injury to the surgeon or operating room personnel [1,6,7]. Suture areas can also be a site for infection and inflammation, which will lead to more complications and require additional treatment [6]. After operations, sutures and other fasteners have a tendency to loosen and possibly break, which entails extra treatment to fix these problems [1].…”
Section: History Of Silver Nanoparticlesmentioning
confidence: 99%
“…For ocular surgeries, suturing corneas often produces asymmetrical healing which results in a regular or an irregular astigmatism [6]. Treating this astigmatism would require more complicated surgery or a pair of corrective spectacles.…”
Section: Technical Importance Of Tissue Adhesivesmentioning
confidence: 99%
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