Desmoid tumor subsequent to resection of a gastrointestinal stromal tumor

Vendrell, Jean-François; Mazars, Romain; Funakoshi, Natalie; Ramos, Jeanne; Gallix, B.; Navarro, Francis

doi:10.1016/j.ejrex.2007.11.001

Cited by 4 publications

(4 citation statements)

References 10 publications

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“…Table 2 summarizes 27 previously reported cases of DT after GIST[3,5-9]. The study population was predominantly male (one case showed no gender data), and the median age of the included patients was 58 years (range: 34-74 years).…”

Section: Discussionmentioning

confidence: 99%

“…1Previous case reports[5-9] and cases with desmoid tumor after gastrointestinal stromal tumor [3]. 2Available previous data ( n = 6).3Abdominal wall ( n = 2) and thigh ( n = 1).4Available previous data ( n = 6).GIST: Gastrointestinal stromal tumor; DT: Desmoid tumor.…”

Section: Discussionmentioning

confidence: 99%

“…In cases of postoperative occurrence, intra-abdominal DT should be distinguished from the recurrence or progression of previous neoplasms. Cases of postoperative DT mimicking GIST have been reported[5-9]. Meanwhile, secondary malignancy may be a differential diagnosis in patients with GIST following the development of a new single lesion.…”

Section: Introductionmentioning

confidence: 99%

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Intra-abdominal desmoid tumors mimicking gastrointestinal stromal tumors —8 cases: A case report

Kim

Ryu

Park

et al. 2019

WJG

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BACKGROUND Intra-abdominal desmoid tumors (DTs) can mimic recurrence or progression of gastrointestinal stromal tumors (GISTs). Differential diagnosis is important to avoid unnecessary or inappropriate treatment. CASE SUMMARY All 8 patients experienced surgical resection of GIST, and median time to diagnosis of DT was 1.8 years after surgical resection. All sites of DT were in the peritoneum around the surgical sites of GIST. The following clinical suspicion coupled with radiological findings contributed to the suspicion of intra-abdominal DTs: (1) Occurrence of a new single lesion in the peritoneum around the surgical sites of GIST; (2) uncontrolled lesion with imatinib while other lesions being controlled with imatinib; (3) well-defined ovoid shaped lesion with delayed or mild enhancement and absence of necrosis, hemorrhage, and cystic change on computed tomography; and (4) a lesion showing mild or no hypermetabolic activity on 18 fluorodeoxyglucose-positron emission tomography, contrary to initially hyperactive lesion of GIST. All DTs were surgically removed except for one unresectable DT and only one DT recurred at another site of peritoneum, which was also surgically removed. CONCLUSION Intra-abdominal DT should be a differential diagnosis for a new single lesion in patients with GIST.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Intra-abdominal desmoid tumors mimicking gastrointestinal stromal tumors —8 cases: A case report

Kim

Ryu

Park

et al. 2019

WJG

View full text Add to dashboard Cite

show abstract

“…12 , 16 , 17 Our literature search yielded one previous report of a desmoid tumor arising in the site of a previously excised GIST. 18 GISTs and desmoid tumors share a common stromal origin but are diverse histologically, genetically, and biologically. Nevertheless, surgical trauma at the GIST excision site may predispose to the development of the desmoid tumor.…”

Section: Discussionmentioning

confidence: 99%