Desmoid Tumors: A Clear Perspective or a Persisting Enigma? A Case Report and Review of Literature

Mishra, Debi Prasad; Rout, Suman Saurav

doi:10.14740/wjon961w

Cited by 4 publications

(4 citation statements)

References 45 publications

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“…DF most commonly localizes to the abdominal wall, intestinal mesentery, or shoulder girdle 4 . In the rare occasions when DF occurs in retroperitoneum, it is usually within the clinical context of a syndrome such as familial polyposis coli/familial adenomatous polyposis (FAP) or Gardner’s syndrome, especially if the patient has a history of abdominal surgery 1 . It usually arises from the deep musculoaponeurotic planes such as muscle fascia, tendons, and aponeurosis 2 .…”

Section: Discussionmentioning

confidence: 99%

“…We report two cases of sporadic DF that is not associated with previous abdominal surgeries or Gardner’s syndrome. Most cases reported in literature identify positive family history of colorectal cancer in cases of sporadic DF and even syndromic DF 1 , 11 . However, in both cases, we report they had a positive family history of cancer other than colorectal, pancreatic, and breast.…”

Section: Discussionmentioning

confidence: 99%

“…Desmoid-type fibromatosis (DF), also known as desmoid tumor or aggressive fibromatosis (AF), is a rare entity on the soft tissue sarcomas (STS) spectrum of tumors accounting for only 3% of all STSs and 0.03% of all neoplasms. Desmoid tumors are mesenchymal in origin and tend to occur in deep soft tissues 1 . DF most commonly occurs in the anterior abdominal wall and shoulder girdle, while a sporadic occurrence in the retroperitoneum is quite rare 2 .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Retroperitoneal desmoid-type fibromatosis: a case report

Charif

Tarhini

Dushfunian

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Desmoid-type fibromatosis (DF) is a rare subtype of soft tissue sarcomas that most commonly occurs in the anterior abdominal wall. When occurring in the retroperitoneum, DF is usually part of familial syndromes while only rarely sporadic. This makes it imperative to report any instance of experience with DF and the oncological outcomes of the different approaches to management. We report two cases of sporadic and severe DF occurring in the retroperitoneum at our institution. Case presentation: The first case is a male that presented with urinary obstruction symptoms and underwent surgical resection of the tumor that extended into the left kidney. The second case is a female with a history of recurrent desmoid tumors of the thigh and was incidentally diagnosed with retroperitoneal DF on imaging. She underwent tumor resection and radiotherapy; however, the tumor recurred with urinary obstruction symptoms that required another surgical resection. Histopathological characteristics and radiological imaging of both cases are described below. Clinical discussion: Desmoid tumors often recur, thus significantly influencing the quality of life which is reflected in one of our cases. Surgery remains a mainstay treatment, and both cases presented in this report required surgical resection of the tumors as symptomatic and curative measures. Conclusion: Retroperitoneal DF is a rare entity, and our cases add to the scarce literature available on the topic, which may well contribute to the formulation of practice-changing recommendations and guidelines focused on this rare variant of DF.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%