Desmoid tumour of the chest wall

Lamboley, J.-L.; Moigne, F. Le; Proust, C.; Thivolet‐Béjui, F.; Tronc, François; Revel, D.; Douek, P.

doi:10.1016/j.diii.2012.03.026

Cited by 8 publications

(3 citation statements)

References 7 publications

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“…[ 8 ] The gene mutations were associated with nuclear accumulation of beta-catenin leading to the of fibroblastic proliferation. [ 9 ] Estrogen and antiestrogen binding sites have been found in desmoid tumors and anti-estrogen therapy has been proved to be effective. [ 10 ] Additionally, the initiation of desmoid tumors may be associated with trauma and surgery.…”

Section: Discussionmentioning

confidence: 99%

Desmoid fibromatosis in the foot

Liu¹,

Lü

2018

Medicine

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Rationale:Desmoid fibromatosis is a rare benign neoplasm arising from musculoaponeurotic structures with the potential to infiltrate local tissues and recur locally. While the commonly affected regions are the shoulder, chest wall and back, thigh, head and neck, localization in the foot is rare and only a few cases have been reported. Deep-seated lesions of foot tend to spread along the fascia and nerve or tendon sheaths.Patient concerns:We present a case of a 41-year-old female with a 3 years history of a slowly enlarging painful mass in the right foot.Diagnoses:Desmoid fibromatosis was diagnosed based on clinical manifestations, imaging findings and pathological examinations.Interventions:The patient was treated by local incomplete resection.Outcomes:The patient recovered well postoperatively and was well followed up at our outpatient department with no evidence of recurrence during 16 months of follow-up after local excision.Lessons:Surgical excision is recommended for symptomatic lesions located in the foot. However, it is difficult to excise thoroughly and periodic follow-up is needed to monitor for recurrence. Further study is warranted to determine whether patients benefit more from function preservation instead of complete resection.

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Section: Discussionmentioning

confidence: 99%

Desmoid fibromatosis in the foot

Liu¹,

Lü

2018

Medicine

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“…For example, in patients affected by FAP or Gardner's syndrome, a mutation in the APC gene has been identified, while in the sporadic forms, there appears to be a mutation in the gene that codes for the β-catenins. The two mutations cause an increase in the concentration of intracellular β-catenins, which induces a boost in fibroblastic proliferation (7).…”

Section: Discussionmentioning

confidence: 99%

Extra-abdominal fibromatosis: Clinical and therapeutic considerations based on an illustrative case

Fornaro

Caratto

et al. 2015

Oncology Letters

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Abstract. Extra-abdominal fibromatosis is a rare, benign disease that is characterized by a local but not metastatic invasivity. In particular, desmoid tumors of the chest wall represent only 10-20% of all deep fibromatoses. The disease occurs more often in females and has a higher incidence between puberty and the fourth decade of life. The present study reports the case of a 34-year-old female who came to our attention due to a voluminous mass in the right subcostal region. The magnetic resonance imaging of the upper abdomen confirmed the presence of a neoplasm localized between the anterior hepatic margin and the right costal plane. Through a right subcostal laparotomy, the voluminous 95x45x94-mm neoplasm was excised. Histological examination showed evidence consistent with extra-abdominal fibromatosis. The patient has not shown recurrence of the disease for 4 years since the surgery. Overall, radical surgery with disease-free resection margins is the prime treatment option for this disease. Other therapeutic options, such as radiotherapy, hormonal therapy or treatment with imatinib mesylate, can also be considered in certain cases.

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“…A high T2-SI is seen in lesions with a high cellularity or myxoid component, whereas low SI is found if lesions predominantly contain collagen. Contrast enhancement is variable in both CT and MRI imaging [22][23][24].…”

Section: Desmoid-type Fibromatosismentioning

confidence: 99%

Tumor and tumorlike conditions of the pleura and juxtapleural region: review of imaging findings

et al. 2021

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Pleural lesions form a diagnostic challenge for the radiologist. Whereas lesions can be initially detected on chest radiographs, CT and MRI imaging are the imaging modalities of choice for further characterization. In a number of cases, imaging findings can be relatively specific. In general unfortunately, imaging findings are rather aspecific. Evolution and extrathoracic imaging findings are important clues toward the diagnosis.

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Desmoid tumour of the chest wall

Cited by 8 publications

References 7 publications

Desmoid fibromatosis in the foot

Desmoid fibromatosis in the foot

Extra-abdominal fibromatosis: Clinical and therapeutic considerations based on an illustrative case

Tumor and tumorlike conditions of the pleura and juxtapleural region: review of imaging findings

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