Desmoid tumours of the anterior abdominal wall

Sutton, Richard; Thomas, Joseph

doi:10.1053/ejso.1999.0664

Cited by 48 publications

(21 citation statements)

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“…Patients with FAP have a 1,000-fold increased risk for desmoid tumors as compared to the general population. Women are more frequently affected, with a female to male incidence ratio of 5:1 [11,12]. Desmoids may occur in the extremities (commonly around limb girdles), the abdominal wall (frequently found in women), the bowel, and the mesentery (commonly associated with FAP) [13].…”

Section: Discussionmentioning

confidence: 99%

Full-term gestation and transvaginal delivery after wide resection of an abdominal desmoid tumor during pregnancy

et al. 2005

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A 29-year-old female was diagnosed with a symptomatic, extra-abdominal desmoid tumor during the first trimester of pregnancy. Computerized tomography (CT) and transabdominal ultrasound (US) noted a mass within the left rectus sheath measuring up to 15 cm in greatest diameter, with mild compression of the uterus. Preoperative diagnosis was confirmed by core-needle biopsy of the lesion. At 20-weeks gestation, wide local resection of the tumor with disease-free margins, as well as abdominal wall reconstruction with polytetrafluoroethylene (PTFE) mesh was successfully undertaken. Histological examination of the tumor ex vivo confirmed that the lesion was a desmoid tumor consisting of spindle cells with dense infiltrating collagenous fibers. Subsequent to her resection, the patient completed a full-term pregnancy without complication, and proceeded with a complication-free transvaginal delivery at 39 weeks. This case illustrates the probable contribution of estrogens towards desmoid tumor development, the durability of abdominal wall reconstruction when subjected to the extraordinary strain of both a gravid uterus and labor, as well as the safety and efficacy of aggressive surgical therapy during pregnancy.

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Section: Discussionmentioning

confidence: 99%

Full-term gestation and transvaginal delivery after wide resection of an abdominal desmoid tumor during pregnancy

et al. 2005

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“…Reconstruction was with two layers of polypropylene mesh (Marlex TM ; Bard, Galway, Ireland) as described previously 10 . Whenever possible the greater omentum was sutured to the margins of the defect to produce a 'neoperitoneum' and to separate bowel from mesh.…”

Section: Aggressive Fibromatosis Of the Abdominal Wallmentioning

confidence: 99%

Aggressive fibromatosis of the abdominal wall, limbs and limb girdles

Phillips¹,

A’Hern

Thomas³

2004

British Journal of Surgery

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“…The excision should be completed with a one cm margin. A mesh can be used to cover the defect if required [46] . For intra-abdominal desmoids surgery should only be used in specific circumstances.…”

Section: Managementmentioning

confidence: 99%

Updates on abdominal desmoid tumors

Rampone¹

2007

WJG

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Desmoid tumor is a monoclonal, fibroblastic proliferation arising in musculoaponeurotic structures. This connective tissue hyperplasia infiltrates locally, recurs frequently after resection but does not metastasize. Abdominal desmoid occurs sporadically, in association with some familial syndromes and often represents a clinical dilemma for surgeons. The enigmatic biology and anatomical location of abdominal desmoids make treatment recommendations difficult. This distinct pathological entity is reviewed with a specific focus on aetiology and management.

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Desmoid tumours of the anterior abdominal wall

Cited by 48 publications

References 0 publications

Full-term gestation and transvaginal delivery after wide resection of an abdominal desmoid tumor during pregnancy

Full-term gestation and transvaginal delivery after wide resection of an abdominal desmoid tumor during pregnancy

Aggressive fibromatosis of the abdominal wall, limbs and limb girdles

Updates on abdominal desmoid tumors

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