Desmoplastic fibroma of the frontal bone

Abstract

Desmoplastic fibroma is a benign but locally aggressive tumor arising usually from the mandible, pelvis and long bones with a potential for recurrence. We report a case of desmoplastic fibroma of the frontal bone in a young male.

Desmoplastic Fibroma of the Pediatric Cranium: An Aggressive Skull Tumor with Local Recurrence

“…DFs are benign but have locally aggressive features; they have not been reported to metastasize, 5 , 11) but tend to recur locally as in the present case. The Second Edition of the World Health Organization histologic classification of bone tumors designated DFs as intermediate group tumors because of this characteristic.…”

“…In addition to the characteristic findings of MRI mentioned earlier, in some cases, internal flow voids of the intratumoral vessels have been noted on T 2 -weighted images, 16 , 18) and in two cases the lesion had extended beyond the dura. 5 , 11) However, these radiological findings are not specific for DFs, and this fact makes diagnosis difficult. The differential diagnosis includes eosinophilic granuloma, cavernous hemangioma, fibrous dysplasia, fibrosarcoma, chondromyxoid fibroma, giant cell tumor, simple bone cyst, aneurysmal bone cyst, chondrosarcoma, invasive meningioma, en-bloc meningioma, and metastasis.…”

“…25) However, other reports have suggested the need for wide excision. 11 , 26) The recurrence rates have been reported as 100% after biopsy, 27) 42–55% after curettage, 26 , 27) 72% after excision, 27) 8.3–17% after partial resection, 27 , 28) and 0% after wide resection. 14 , 27) The potential benefit of adjuvant therapy, including radiotherapy or chemotherapy, has not yet been established.…”

Desmoplastic Fibroma of the Cranium in a Young Man

“…Clinical symptoms include headache, cranial asymmetry, ear symptoms, and skull mass. Intracranial involvement was reported in one case, but brain parenchymal invasion has not been reported17).…”

Fibro-osseous lesion of the cranium in an adolescent patient

“…Gardini et al . first described a case of DF affecting the skull in 1978 and a total of 20 cases have been reported[ 2 6 7 8 9 11 12 15 17 18 21 22 23 24 26 31 32 ] with only 8 of these involving pediatric patients. [ 2 7 11 22 31 32 ] DF of the skull tends to have a higher incidence in females.…”