Desmoplastic Trichilemmoma—A Report of Successful Treatment with Mohs Micrographic Surgery and a Review and Update of the Literature

Afshar, Maryam; Lee, Robert A.; Jiang, Shang I Brian

doi:10.1111/j.1524-4725.2012.02514.x

Cited by 13 publications

(21 citation statements)

References 18 publications

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“…[10][11][12][13] In patients with lymph node metastases, the mortality rate is high at 67%, and the chance of distant metastasis is about 11% to 12%. 22 Given the aggressive nature of EPC and high rate of local recurrence, the superior margin control for contiguous tumors available with MMS may be an ideal treatment modality. Some reported treatment options include wide excision, chemotherapy, radiation therapy, and Mohs micrographic surgery (MMS).…”

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confidence: 99%

Mohs Micrographic Surgery for Eccrine Porocarcinoma

Song

Lee

Hamman

et al. 2015

Dermatologic Surgery

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confidence: 99%

Mohs Micrographic Surgery for Eccrine Porocarcinoma

Song

Lee

Hamman

et al. 2015

Dermatologic Surgery

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“…'s are indeed very infrequent tumours. 6,15 The total of only 81 cases reported worldwide up to 2012 may in fact represent an underestimation of the actual prevalence of these tumours. It has been reported to occur in several ethnicities, seeming to be more prevalent in males and to favor the 5 th -6 th decades of life.…”

Section: Discussionmentioning

confidence: 99%

“…As far as location, DT`s seem to predominate on the facial area, although extrafacial locations have also been described. 15 Clinically, its presentation is quite non-specific, either as a lobular or diffuse thickening of a previous NS or as newly superimposed translucid or keratotic papules and nodules. In fact, desmoplastic trichilemmomas in this context can be easily taken for viral warts, intradermal nevi, seborrheic keratoses, BCC, SCC or cutaneous horns, 2,3 as such requiring histological examination in each and every case.…”

Section: Discussionmentioning

confidence: 99%

“…In what concerns DT treatment, although usually benign, its potential coexistence with atypical basaloid cell proliferations including CBC, makes Mohs surgery (for both adequate margin control and tissue sparing benefits) 15,21 or complete surgical excision with pathological confirmation of clear margins the treatments of choice. 22 In summary, a case of a patient with a desmoplastic trichilemmoma arising in a nevus sebaceous of the scalp is reported.…”

Section: Discussionmentioning

confidence: 99%

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Triquilemoma Desmoplástico em Nevo Sebáceo do Couro Cabeludo

Tavares‐Bello

Fernandes

2016

SPDV

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RESUMO -Descrito originalmente por Jadassohn em 1895, foi apenas em 1932 que a designação "nevo sebáceo" foi introduzida, por Robinson. Trata-se de um hamartoma congénito relativamente prevalente que, classicamente, evolui por fases de crescimento e maturação (classicamente estão descritas 3 fases: infância <12; adolescência 12-18; adultos >18) e que, do 4º ao 7º decénios pode originar, em 10-30% dos casos), várias neoplasias epiteliais. Muito raramente reportados neste contexto, os triquilemomas são tumores anexiais benignos que se originam ou diferenciam no epitélio da bainha radicular externa folicular. Habitualmente solitários, podem apresentar-se clinicamente como pápulas translúcidas ou queratósicas faciais, em particular na proximidade da pirâmide nasal e dos lábios. A rara variante histológica "triquilemoma desmoplásico" pode simular clinicamente basaliomas (CBC), carcinomas espinhocelulares (CEC), nevos intradérmicos, verrugas virais, cornos cutâneos ou hiperplasias sebáceas e, histologicamente, evocar variantes desmoplásicas de CBCs, CECs e de carcinomas triquilémicos. É apresentado caso de doente eurocaucasiano de 56 anos de idade que apresentava pápulas e nódulos translúcidos assintomáticos, desenvolvidos num nevo sebáceo do couro cabeludo. O estudo histológico revelou uma proliferação lobular com as características clássicas do triquilemoma desmoplásico no seio de um hamartoma sebáceo. O caso é ilustrado iconograficamente e a literatura relevante é sumariamente revista. PALAVRAS-CHAVE -Nevo; Neoplasias das Glândulas Sebáceas; Neoplasias da Pele. Desmoplastic Trichilemmoma arising on a Nevus Sebaceous of the Scalp ABSTRACT -Originally described by Jadassohn in 1895, it was not until 1932 that the term "nevus sebaceous" was introduced by Robinson. It is a prevalent benign congenital hamartoma that classically evolves through discrete phases of growth and that

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“…There are also reports of association of desmoplastic trichilemmoma with atypical basaloid proliferations, such as basal-cell carcinoma, maintaining the importance of diagnostic confirmation by histopathological analysis of the lesion. 8,10 …”

Section: Discussionmentioning

confidence: 99%