Desmoplastic variant of ameloblastoma in Malaysians

Ng, Kok Han; Siar, Chong Huat

doi:10.1016/0266-4356(93)90064-4

Cited by 41 publications

(39 citation statements)

References 13 publications

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“…Sun et al (2) (2009) identified a 15.9% rate of recurrence in DA cases treated by enucleation and/or curettage, with an average recurrence period of 36.9 months. The majority of DA cases reported in the literature have been treated by resection, most likely due to ill-defined borders, thus suggesting an infiltration process and an aggressive biological behavior, which has also been reported by some authors (3,15). In the present case report, the patient is currently showing no signs of recurrence.…”

Section: Case Reportsupporting

confidence: 58%

“…In additional, DA is a rare form of tumor and has been described in 115 cases in English literature (2). Radiographically, 50% of DA shows an image suggesting a benign fibro-osseous lesion (2,3). Eventually, the clinical-radiographic features of DA may be ignored by surgeons and radiologists who more easily recognized the solid/multicystic variant of the ameloblastoma.…”

Section: Introductionmentioning

confidence: 99%

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A case report of desmoplastic ameloblastoma

Amaral¹,

Freire-Maia²,

Serpa³

et al. 2010

J Clin Exp Dent

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Ameloblastomas are the most common benign neoplasm of odontogenic nature. Desmoplastic ameloblastoma (DA) was included in the World Health Organization Classification of Head and Neck Tumors (WHO-2005) as a variant of ameloblastoma with specific clinical, image, and histological features. This case report focuses on a DA which occurred in the mandible of a 25 year-old man. The main signals and symptoms included painless swelling with buccal expansion and tooth displacement. Panoramic and periapical radiographs and cone-bean computed tomography demonstrated an image mimicking a benign fibro-osseous lesion. The lower border of the mandible was not involved, but tooth displacement could be observed. An incisional biopsy was performed, and the DA was diagnosed. A marginal resection, maintaining the lower border of the mandible, was performed on teeth 46 to 31. The post-operative period was uneventful. The patient is undergoing routine follow-up and is currently free of disease.

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Section: Case Reportsupporting

confidence: 58%

Section: Introductionmentioning

confidence: 99%

A case report of desmoplastic ameloblastoma

Amaral¹,

Freire-Maia²,

Serpa³

et al. 2010

J Clin Exp Dent

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“…Duration of the desmoplastic lesions can extend from 1 month all the way to 20 years 18,19 , with a mean time of 23 months 18 . In the present investigation, solid and desmoplastic lesions had a mean development time of 36.9 months and 18 months, respectively.…”

Section: Hybrid Lesionmentioning

confidence: 99%

Ameloblastomas sólidos: estudo retrospectivo clínico e histopatológico em 54 casos

Fulco¹,

Nonaka²,

Souza³

et al. 2010

Braz. j. otorhinolaryngol. (Impr.)

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Recent ly, the World Health Organization (WHO) excluded the desmoplastic pattern from the histopathological spectrum of solid ameloblastomas and classified it as a distinct variant, named desmoplastic ameloblastoma. Aim: To perform a retrospective analysis of the clinicopathologic aspects in a case series of solid ameloblastomas. Study design: Crosssectional cohort study. Materials and methods: Data regarding age, gender, location and clinical characteristics were retrieved from patient records. Histological sections were evaluated regarding existing histological patterns and the predominant histological pattern. Cases were classified according to the study of Waldron and El-Mofty (1987) and the WHO classification of 2005. Results: A total of 54 cases were identified, with similar gender distribution and a mean age of 38.3 years. Fifty three cases (98.1%) affected the mandible. Forty nine cases (90.8%) were classified as solid ameloblastomas, 3 (5.6%) as desmoplastic ameloblastomas, and 2 (3.7%) as hybrid lesions. The most frequent histological patterns in solid ameloblastomas were follicular (77.6%), acanthomatous (69.4%), and plexiform (65.3%). Focal areas of desmoplastic ameloblastomas were identified in 11 solid ameloblastomas (22.4%). Conclusion: Despite its characterization as a distinct variant, our results revealed that focal areas of desmoplastic ameloblastomas can be observed with some frequency in conventional ameloblastomas.

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“…Ng & Siar 16 using various immunohistochemical techniques demonstrated that the tumor cells of desmoplastic ameloblastoma showed variable expression of S-100 proten and desmin. Similarly, it has been reported that connective tissue stroma in desmoplastic ameloblastoma exhibited a strong positive reaction for collagen type VI.…”

Section: Discussionmentioning

confidence: 99%