“…Fourth, the algorithm is tested on new unseen datasets to examine validity (ie, correspondence between human coded "ground truth" and algorithm). This approach has been used to automate video-based detection of human motion [27][28][29][30][31] and behaviors relevant to autism, 32,33 obsessive-compulsive disorder, 34 neurodevelopmental risk, 35 Parkinson's disease, 36 bradykinesia, 37,38 hypomimia, 39 seizure, 40 infant neuromotor impairment, 41 and depression. 42 Fully automated measurement has several advantages: algorithms are efficient, immune to human limitations (eg, training burden, drift, reactivity, fatigue, distraction), and can measure aspects of movement that humans struggle to quantify (eg, movement amplitude and velocity).…”