Detection and characterization of colitis‐associated cancer/dysplasia: Based on reports from the JDDW 2017 and meta‐analyses of prospective studies concerning endoscopic procedure

Endoscopic diagnosis and treatment of ulcerative colitis‐associated neoplasia

“…In previous clinical studies on the utility of NBI colonoscopy for detecting UCAN, surveillance colonoscopy with NBI did not yield satisfactory results, and no significant difference in the ability to detect UCAN was found between NBI and WLE . An advantage of NBI magnification is that visualization can be achieved without dye spraying, potentially reducing the cost of examination.…”

“…An advantage of NBI magnification is that visualization can be achieved without dye spraying, potentially reducing the cost of examination. A new‐generation NBI system with improved brightness has been developed, and prospective trials for the diagnosis of UCAN showed that surveillance colonoscopy with pancolonic NBI observation was not inferior to that with panchromoendoscopy, and it was also found to be a time‐saving procedure . Surface pattern, as determined using NBI magnifying colonoscopy, is a useful finding for differentiation between UCAN and non‐neoplastic lesions.…”

“…In previous clinical studies on the utility of NBI colonoscopy for detecting UCAN, surveillance colonoscopy with NBI did not yield satisfactory results, and no significant difference in the ability to detect UCAN was found between NBI and WLE. 2,3 An advantage of NBI magnification is that visualization can be achieved without dye spraying, potentially reducing the cost of examination. A new-generation NBI system with improved brightness has been developed, and prospective trials for the diagnosis of UCAN showed that surveillance colonoscopy with pancolonic NBI observation was not inferior to that with panchromoendoscopy, and it was also found to be a timesaving procedure.…”

“…Hence, surveillance colonoscopy should be carried out in patients with UC . However, non‐polypoid UCAN is more difficult to detect than polypoid UCAN because non‐polypoid UCAN often presents as flat, multifocal, and anaplastic lesions that may not be readily distinguishable from the surrounding inflamed mucosa . Several recent trials have evaluated chromocolonoscopy, magnifying colonoscopy, or image‐enhanced endoscopy (IEE) for the detection of UCAN …”

“…1 However, non-polypoid UCAN is more difficult to detect than polypoid UCAN because non-polypoid UCAN often presents as flat, multifocal, and anaplastic lesions that may not be readily distinguishable from the surrounding inflamed mucosa. [2][3][4] Several recent trials have evaluated chromocolonoscopy, magnifying colonoscopy, or image-enhanced endoscopy (IEE) for the detection of UCAN. 2,3 According to the Surveillance for Colorectal Endoscopic Neoplasia Detection and Management in Inflammatory Bowel Disease Patients: International Consensus Recommendations (SCENIC) guidelines published in 2015, 4 a lesion can be characterized as "endoscopically resectable" when distinct margins can be identified, the lesion appears to be completely removed on visual inspection after endoscopic resection, histological examination of the resected specimen yields results consistent with complete removal, and biopsy specimens taken from the mucosa immediately adjacent to the resection site are free of dysplasia on histological examination.…”