Detection and characterization of early malignancy in the esophagus: What is the best management algorithm?

The importance of a second opinion in the diagnosis of Barrett’s esophagus: a “real life” study

“…In fact, since it is well known that Barrett's epithelium may progress to adenocarcinoma over a period of time (34,35), it is of paramount importance to detect the early phases of neoplastic transformation, that is, LGD. Since patients with BE usually enter a surveillance program (36), and the finding of dysplasia prompts repeated endoscopic and pathologic controls (37), thus raising the health costs (38), efforts should be made not to overemphasize the diagnosis of dysplasia in this setting. On the other hand, further efforts should be made to obtain diag- LGD in BE LGD in BE 2 C3M4…”