Device wearability and operating time are trending topics in recent state-of-art works on surface ElectroMyoGraphic (sEMG) muscle monitoring. No optimal trade-off, able to concurrently address several problems of the acquisition system like robustness, miniaturization, versatility, and power efficiency, has yet been found. In this tutorial we present a solution to most of these issues, embedding in a single device both an sEMG acquisition channel, with our custom event-driven hardware feature extraction technique (named Average Threshold Crossing), and a digital part, which includes a microcontroller unit, for (optionally) sEMG sampling and processing, and a Bluetooth communication, for wireless data transmission. The knowledge acquired by the research group brought to an accurate selection of each single component, resulting in a very efficient prototype, with a comfortable final size (57.8 mm x 25.2 mm x 22.1 mm) and a consistent signal-to-noise ratio of the acquired sEMG (higher than 15 dB). Furthermore, a precise design of the firmware has been performed, handling both signal acquisition and Bluetooth transmission concurrently, thanks to a FreeRTOS custom implementation. In particular, the system adapts to both sEMG and ATC transmission, with an application throughput up to 2 kB s −1 and an average operating time of 80 h (for high resolution sEMG sampling), relaxable to 8 B s −1 throughput and about 230 h operating time (considering a 110 mAh battery), in case of ATC acquisition only. Here we share our experience over the years in designing wearable systems for the sEMG detection, specifying in detail how our event-driven approach could benefit the device development phases. Some previous basic knowledge about biosignal acquisition, electronic circuits and programming would certainly ease the repeatability of this tutorial.