Detection and determination of spectinomycin and lincomycin in poultry muscles and pork by ASE-SPE-GC–MS/MS

Guo, Yawen; Xie, Xiulan; Diao, Zhixiang; Wang, Yajuan; Wang, Bo; Xie, Kaizhou; Wang, Xutang; Zhang, Peiyang

doi:10.1016/j.jfca.2021.103979

Cited by 18 publications

(13 citation statements)

References 21 publications

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“…(HPLC) High-performance liquid chromatography is a highly precise, accurate, and robust technique for materials analysis [13]. Using HPLC in lincomycin determination is accurate and more economical when compared with other studies using LC-MS/MS and GC-MS/MS [14][15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Validation of A Developed Analytical Chromatographic Method for Liposomal Lincomycin Quantification in The Biological Matrices of Broiler Chickens

Elghweet,

Fadel,

Ramadan

et al. 2025

Egyptian Journal of Veterinary Sciences

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HIS study aimed to validate an accurate, precise and simple method. followed green chemistry to extract lincomycin from its liposomal coat and determined its levels in the serum and tissues of broiler chickens. Liposomes are natural compounds used for drug delivery. Nanomaterials with antibiotics aim to improve antibiotic effects and reduce side effects. The global trend follows the green analytical chemistry guidelines for the development of analytical methods to quantify materials.The extraction depended on ultracentrifugation of serum samples and solvent extraction with low centrifugation power for tissue extraction. A C18 column with an isocratic mobile phase consisting of acetone to acidified HPLC water with glacial acetic acid (2%) in the following ratio (16:84) was used. UV detector was set at 210 nm to detect lincomycin.The method had a short retention time of 3.227 min. The relative standard deviation (RSD) was < 2%. High recoveries ranged from 90.2 up to 102.1% in the different extracted biological samples. The low limits of detection were 0.025 and 0.2 µg/gm, which measure the high sensitivity level of the validated method and quantification ranged from 0.077 to 0.67 µg/gm. The pooled RSD for robustness of the lincomycin assay did not exceed 3.3 %. This method follows green chemistry, which is in agreement with economic requirements of developing countries. It was efficient for the separation of lincomycin from the nanoliposome coat. It is selective and sensitive, reliable, reproducible, precise, and accurate according to the guidelines for the validation of the analytical methods.

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Section: Introductionmentioning

confidence: 99%

Validation of A Developed Analytical Chromatographic Method for Liposomal Lincomycin Quantification in The Biological Matrices of Broiler Chickens

Elghweet,

Fadel,

Ramadan

et al. 2025

Egyptian Journal of Veterinary Sciences

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“…Up to now, a wide variety of analytical methodologies have been developed for Lin determination, such as HPLC, 4,5 enzyme-linked immunosorbent assay, 6 molecular imprinting, 7 fluorescence methods, 8 and mass spectrometry. 9,10 However, these methods have some shortcomings of time-consuming pretreatment, requirement of skilled operators, and unsatisfactory sensitivity.…”

Section: Introductionmentioning

confidence: 99%

Supersensitive detection of lincomycin with an ECL aptasensor based on the synergistic integration of gold-functionalized upconversion nanoparticles and thiolated 3,4,9,10-perylene tetracarboxylic acid

Chen,

Wen,

Shan

et al. 2024

Analyst

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“…24,25 Therefore, the European Union has stipulated maximum residue limits (MRLs) of Lin in milk as 150 μg/kg. 26 Herein, Eu MOFs and Au−Pt bimetallic NRs were explored to design an aptasensor for the Lin assay (Scheme 1). Here, because of their high catalytic activity and innate luminescence excellence through 4f−4f transitions, Eu MOFs worked as a scaffold to improve ECL performance in immunodetection.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Lincomycin (Lin), an antibiotic produced by the fermentation of Streptomyces lincomi, is a strong bactericide against Gram-positive bacteria, some anaerobic bacteria, and mycoplasma. , However, Lin remaining in milk would cause renal dysfunction for human health and increase the drug resistance of Gram-positive bacteria after entering the human body through the food chain. , Therefore, the European Union has stipulated maximum residue limits (MRLs) of Lin in milk as 150 μg/kg …”

Section: Introductionmentioning

confidence: 99%

Plasmon-Enhanced Electrochemiluminescence of PTP-Decorated Eu MOF-Based Pt-Tipped Au Bimetallic Nanorods for the Lincomycin Assay

Luo

Can

et al. 2022

ACS Appl. Mater. Interfaces

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Plasmonic bimetal nanostructures can be employed to amplify electrochemiluminescence (ECL) signals. In this work, a high-performance ECL platform was constructed using a europium metal−organic framework (MOF) as a luminophore and Au−Pt bimetallic nanorods (NRs) as a plasma source. Due to the SPR effect of Au−Pt NRs, the aptasensor exhibits 2.6-fold ECL intensity compared to that of pure polyaniline (PANI)-decorated perylene tetracarboxylic dianhydride (PTCA)/Eu MOF. Moreover, decoration with PTP greatly enhances the conductivity and stability of Eu MOF, resulting in sizeable plasmon-enhanced electrochemical luminescence. The as-designed plasmon-enhanced ECL aptasensor displayed highly sensitive detection for lincomycin (Lin). The asproposed aptasensor could quantify Lin from 0.1 mg/mL to 0.1 ng/mL with a limit of detection (LOD) of 0.026 ng/mL.

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Detection and determination of spectinomycin and lincomycin in poultry muscles and pork by ASE-SPE-GC–MS/MS

Cited by 18 publications

References 21 publications

Validation of A Developed Analytical Chromatographic Method for Liposomal Lincomycin Quantification in The Biological Matrices of Broiler Chickens

Validation of A Developed Analytical Chromatographic Method for Liposomal Lincomycin Quantification in The Biological Matrices of Broiler Chickens

Supersensitive detection of lincomycin with an ECL aptasensor based on the synergistic integration of gold-functionalized upconversion nanoparticles and thiolated 3,4,9,10-perylene tetracarboxylic acid

Plasmon-Enhanced Electrochemiluminescence of PTP-Decorated Eu MOF-Based Pt-Tipped Au Bimetallic Nanorods for the Lincomycin Assay

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