Detection and Measurement of Fetomaternal Hemorrhage following Diagnostic Cordocentesis

Chitrit, Yvon; Caubel, Patrick; Lusina, Daniel; Boulanger, Marie-Chloé; Balledent, Françoise; Schwinte, Anne Lyse; Herrero, Rafael

doi:10.1159/000020849

Cited by 12 publications

(5 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…With increasing age and decreasing BMD, relative movement between the lag screw and the femoral head has been described, which can lead to cut out of the lag screw particularly in cases of imperfect lag screw positions. 25,26 Although this poses a problem in elderly persons with hip fractures, lag screw cut out was not observed in our study and is typically not observed in younger individuals.…”

Section: Discussionmentioning

confidence: 50%

Biomechanical Evaluation of Interlocking Lag Screw Design in Intramedullary Nailing of Unstable Pertrochanteric Fractures

Hoffmann

Paetzold

Stephan

et al. 2013

Journal of Orthopaedic Trauma

View full text Add to dashboard Cite

The interlocking lag screw design reduced movement of the femoral head and relative movement between fracture fragments. Beyond that the trapezoidal nail design of the Intertan reduced toggling within the trochanteric area and prolonged survival. Although this study showed a decrease in the retention of stability over time, failure did not occur until the equivalent of 2-3 months of reduced physical activity in which healing may have occurred under normal clinical conditions.

show abstract

Section: Discussionmentioning

confidence: 50%

Biomechanical Evaluation of Interlocking Lag Screw Design in Intramedullary Nailing of Unstable Pertrochanteric Fractures

Hoffmann

Paetzold

Stephan

et al. 2013

Journal of Orthopaedic Trauma

View full text Add to dashboard Cite

show abstract

“…Both methods were efficient in proving FMH in the second trimester. Chitrit et al . conducted a study involving 103 diagnoses for cordocentesis without any other associated procedures, at gestational ages of 23–40 weeks, and FMH was investigated using the Kleihauer–Betke test immediately before and after the procedure.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of passage of fetal erythrocytes into maternal circulation after invasive obstetric procedures

Meleti

Oliveira

Júnior

et al. 2013

J of Obstet and Gynaecol

View full text Add to dashboard Cite

Aim: The aim of this study was to evaluate the passage of fetal erythrocytes into the maternal circulation after invasive obstetric procedures, using the Kleihauer-Betke test, flow cytometry and a-fetoprotein concentration in maternal blood. Material and Methods:This was a prospective descriptive study on patients who underwent: amniocentesis, cordocentesis, chorionic villus sample, amniotic infusion, bladder drainage and ventricular-amniotic shunt to investigate the karyotype; treatment for hydrocephalus, oligohydramnios, obstructive uropathy and polyhydramnios; and investigation of lung maturity. Maternal blood samples were collected before and 60 min after the invasive obstetric procedure in order to evaluate the passage of fetal erythrocytes using the Kleihauer-Betke test, flow cytometry and a-fetoprotein concentration. Results: In total, 43 invasive obstetric procedures were performed. The procedures performed were: 27 cases of amniocentesis (62.7%), seven cases of cordocentesis (16.2%), four chorionic villus samples (9.4%), two amniotic infusions (4.7%), two ventricular-amniotic shunts and one bladder drainage (2.3%). After one case of cordocentesis with two puncture attempts via the placenta, a significant increase in fetal erythrocytes was detected using the three methods. After another cordocentesis with one puncture via the placenta, a significant increase in fetal erythrocytes was detected using flow cytometry and a-fetoprotein concentration, but not through the Kleihauer-Betke test. The other 41 samples did not show any significant increase in fetal erythrocytes in the maternal blood. Conclusion: Invasive obstetric procedures performed during prenatal care are safe when performed by experienced professionals with the proper technique, with minimal chance of passage of fetal erythrocytes into the maternal compartment.

show abstract

“…CVS is performed by removing a small sample of the placenta with either a catheter or a needle. For these reasons, both tests might be associated with an increased risk of FMH (4,(11)(12). The aim of our study was to explore if the quantification of fetal erythrocytes in maternal blood could be useful to control FMH as an adverse side effect of these tests to perform a prompt and appropriate management.…”

Section: Discussionmentioning

confidence: 99%

Significance of the volume of fetomaternal hemorrhage after performing prenatal invasive tests

Subirá

Uriel

Ma³

et al. 2010

Cytometry

View full text Add to dashboard Cite

Background: Fetal erythrocytes cross the placenta during gestation, but invasive prenatal procedures might develop into fetomaternal hemorrhage (FMH). We examine whether flow cytometry immunophenotyping might be useful for measuring the volume of FMH after such procedures.Methods: Fetal erythrocytes (%) were determined in 153 pregnant women after amniocentesis (129) and chorionic villous sampling (24) using a monoclonal antibody against fetal hemoglobin. Fetal erythrocytes were identified for their high expression of fetal hemoglobin (HbF 11 ). Blood samples from two control groups, 53 healthy males and 21 pregnant women not submitted to invasive tests, were used to establish normal values of circulating HbF 11 erythrocytes in adults. Results: The highest percentage of HbF 11 erythrocytes in the control groups was 0.015%. The rate of HbF 11 erythrocytes in samples after invasive tests ranged between <0.01% and 0.15%. Seventy-three women (47%) had 0.015% HbF 11 erythrocytes, and this rate was higher in 80. Nine women presented >1 ml of FMH (volume of packed cells corresponding to 0.054-0.15% HbF 11 erythrocytes), but only two had sonographic evidence of bleeding.Conclusions: Most women in our series had a very low volume of FMH after the invasive tests. Acute bleeding should be thoroughly investigated in women with either more than 1 ml of packed cells or more than 0.05% of HbF 11 erythrocytes. Intermediate values between >0.015% and <0.05%, should be carefully considered depending on the week of gestation. Data obtained before 15 weeks might reflect previous cell trafficking between fetus and mother instead of acute hemorrhage. V C 2010 International Clinical Cytometry Society

show abstract

Detection and Measurement of Fetomaternal Hemorrhage following Diagnostic Cordocentesis

Cited by 12 publications

References 17 publications

Biomechanical Evaluation of Interlocking Lag Screw Design in Intramedullary Nailing of Unstable Pertrochanteric Fractures

Biomechanical Evaluation of Interlocking Lag Screw Design in Intramedullary Nailing of Unstable Pertrochanteric Fractures

Evaluation of passage of fetal erythrocytes into maternal circulation after invasive obstetric procedures

Significance of the volume of fetomaternal hemorrhage after performing prenatal invasive tests

Contact Info

Product

Resources

About